Results 241 to 250 of about 218,060 (295)
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang +15 more
wiley +1 more source
Influence of Transformational Leadership Competence on Nurses' Intent to Stay: Cross-Sectional Study. [PDF]
Adalin NM +7 more
europepmc +1 more source
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen +9 more
wiley +1 more source
Epigenetic age and telomere length correlations in pediatric-onset multiple sclerosis. [PDF]
Yang JH +27 more
europepmc +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
A Novel Deep Learning Framework for Liver Fibrosis Staging and Etiology Diagnosis Using Integrated Liver-Spleen Elastography. [PDF]
Yang K, Chen F, Tian A, Deng L, Mao X.
europepmc +1 more source
Membrane‐Mediated Force Transduction Drives Stick‐Slip Motion of Lipid Vesicles
A rotating magnetic field actuates a ferromagnetic particle inside a lipid vesicle, generating internal flows that induce stick‐slip propulsion near a surface. Membrane properties—elasticity, excess area, and phase behavior—modulate this motion by shaping stress dissipation and force transduction.
Paula Magrinya +3 more
wiley +1 more source

