Results 41 to 50 of about 32,688 (228)

(Non-)Regression in EU Lawmaking: the Sustainability Omnibus as a Turning Point?

open access: yesEuropean Journal of Risk Regulation
This article examines the Sustainability Omnibus as a potential turning point in EU lawmaking through the lens of the emerging principle of non-regression in environmental law.
Erriketi Tla da Silva
doaj   +1 more source

The Effects of Models of Dynamic Assessment on EFL Learners’ Writing Apprehension and Writing Self-Efficacy [PDF]

open access: yesJournal of English Language Teaching and Learning
Dynamic assessment (DA) is an innovative way of assessing students’ knowledge. Given the importance of knowing how to reduce writing apprehension and improve writing self-efficacy in language learning, this study investigated the effects of models of DA ...
Zahra Siravand, Abbas Zarei
doaj   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

open access: yesCytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith   +9 more
wiley   +1 more source

Enhancing Asphalt Binder Performance and Storage Stability with Trinidad Lake Asphalt (TLA)

open access: yesApplied Sciences
This study delves into the transformative effects of Trinidad Lake Asphalt (TLA) on asphalt binders, revealing significant improvements in various performance metrics.
Shyaamkrishnan Vigneswaran   +4 more
doaj   +1 more source

TLA+ specifikacijų išskyrimas iš Elixir programos

open access: yesVilnius University Open Series, 2023
Šiame tyrime yra nagrinėjamas metodas, padedantis užtikrinti Elixir programos atitikimą programinės įrangos inžinieriaus kurtai TLA+ specifikacijai.
Deividas Bražėnas, Karolis Petrauskas
doaj   +1 more source

Empirical PK/PD Model for Differentiating Intrinsic Dosing Rules by Therapeutic Indication With Relevance for HIV‐1 Latency Reversal

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Romidepsin (RMD), an FDA‐approved histone deacetylase inhibitor for treating cancer, demonstrates potent latency‐reversing activity in vitro but has yielded suboptimal outcomes in kick‐and‐kill HIV‐cure trials when administered as a 5 mg/m2 infusion.
Lauren A. R. Tompkins   +7 more
wiley   +1 more source

Prime-boost vaccination with toxoplasma lysate antigen, but not with a mixture of recombinant protein antigens, leads to reduction of brain cyst formation in BALB/c mice. [PDF]

open access: yesPLoS ONE, 2015
Infection with the ubiquitous parasite Toxoplasma gondii is a threat for immunocompromised patients and pregnant women and effective immune-prophylaxis is still lacking.Here we tested a mixture of recombinant T.
Angelika Wagner   +7 more
doaj   +1 more source

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard   +3 more
wiley   +1 more source

A more complete TLA [PDF]

open access: yes, 1999
This paper defines a generalization of Lamport's Temporal Logic of Actions. We prove that our logic is stuttering-invariant and give an axiomatization of its propositional fragment. We also show that standard TLA is as expressive as our extension once quantification over flexible propositions is added.
openaire   +2 more sources

Patterns of psychopathology and personal strengths among youth in psychiatric care

open access: yesJCPP Advances, EarlyView.
Abstract Background The American Academy of Pediatrics and the American Academy of Child and Adolescent Psychiatry have declared a National State of Emergency in Children's Mental Health, calling for improved approaches to address youth mental health.
Logan R. Cummings   +78 more
wiley   +1 more source

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