Results 281 to 290 of about 152,328 (305)

TLR2 joins the interferon gang

Nature Immunology, 2009
The induction of type I interferon is a critical checkpoint in antiviral immunity. Toll-like receptor 2 can unexpectedly induce type I interferon in the subset of inflammatory monocytes during infection with vaccinia virus.
Franz Bauernfeind, Veit Hornung
openaire   +1 more source

Megakaryocyte TLR2: immunity bullet?

Blood, 2011
Innate immunity is the host defensive weapon against pathogens and this issue of Blood offers an interesting new bullet for the immune system gun by studying the role of Toll-like receptor 2 (TLR2) in megakaryocytic function; a field previously not explored.
PIGNATELLI, Pasquale, CARNEVALE, Roberto
openaire   +2 more sources

TLR2: for or against Candida albicans?

Trends in Microbiology, 2005
In a recent issue of Trends in Microbiology, Netea and coworkers presented their opinion that toll-like receptors (TLRs) are involved in escape from the defense mechanisms of the host [1]. In their article, the authors clearly identified three major TLR-mediated escape mechanisms that are used by microbial pathogens, such as Yersinia, Mycobacterium and
M Luisa, Gil, Didier, Fradelizi, Daniel, Gozalbo   +2 more
openaire   +2 more sources

Fungal Recognition by TLR2 and Dectin-1

2008
The innate immune system utilizes multiple receptors to recognize fungal pathogens, and the net inflammatory response is controlled by interactions between these receptors. Many fungi are recognized, at least in part, by Toll-like receptor 2 (TLR2) and Dectin-1.
Helen S, Goodridge, David M, Underhill
openaire   +2 more sources

Current Perspectives of TLR2 Signalling in the Retina

Toll-like receptor 2 (TLR2) signalling is crucial in initiating the innate immune response. Under normal conditions, TLR2 can recognise and respond to danger signals in the body and protect against damaging pathogens and molecules. However, dysregulation of this tightly controlled cascade has been implicated in various retinal disorders. There are many
Rachel, Dalton, Sarah, Doyle
openaire   +2 more sources

??????????????? ?????????????????????????? ?????????? TLR2 ???? TLR4 ???? ???????????????????? ???? ?????????????? ???????????????????????????? ????????????????

2014
???????????????????? ?????????????????????? ???????????????????????????????? ?????????????????????? ?????????????????? Arg753Gln ???????? TLR2 ???? Asp299Gly, Thr399Ile ???????? TLR4 ?????????? ????????, ???? ???????????????????? ?? ?????????????????????? ??????????????, ?? ?????????? ??????????????? ?????????????????????????? ???? ?????????????????? ??
openaire   +1 more source

The Role of TLR2 in Infectious Diseases Caused by Mycobacteria: From Cell Biology to Therapeutic Target

Biology, 2022
WanBin Hu, Herman P Spaink
exaly  

TLR2 Gene

2020
openaire   +1 more source

The novel small-molecule antagonist MMG-11 preferentially inhibits TLR2/1 signaling

Biochemical Pharmacology, 2020
Manuela S Murgueitio, Marcel Bermudez, Gerhard Wolber   +2 more
exaly  

Neutralization of pro‐inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis

EMBO Journal, 2016
Tegest Aychek, Ziv Porat, Biana Bernshtein   +2 more
exaly