Results 61 to 70 of about 422,486 (245)

Magnetic characterisation of Tm/Y and Tm/Lu superlattices

open access: yesJournal of Magnetism and Magnetic Materials, 1999
Single-crystal Tm/Y and Tm/Lu superlattices have been grown using molecular beam epitaxy and their chemical structures have been determined using X-ray diffraction. Magnetisation measurements have revealed a more complicated phase diagram than that of pure Tm.
Wilkins, C   +6 more
openaire   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Reviewing the 95 sociotechnical barriers to the decarbonization of buildings

open access: yesNature Communications
Building decarbonization is critical to meet climate goals, given the embodied energy, and material resources needed to construct buildings, their operational energy use, and the need for new facilities for growing populations in addition to retrofitting
Erin Heinz   +3 more
doaj   +1 more source

How Do Methods Assimilating Sentinel-2-Derived LAI Combined with Two Different Sources of Soil Input Data Affect the Crop Model-Based Estimation of Wheat Biomass at Sub-Field Level?

open access: yesRemote Sensing, 2020
The combination of Sentinel-2 derived information about sub-field heterogeneity of crop canopy leaf area index (LAI) and SoilGrids-derived information about local soil properties might help to improve the prediction accuracy of crop simulation models at ...
Andreas Tewes   +6 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Вплив складу супрамолекулярних комплексів зостеран–борна кислота на ефективність ростових процесів злакових культур

open access: yesInnovative Biosystems and Bioengineering, 2019
Проблематика. Бор визнаний важливим мікроелементом для процесів функціонування вищих рослин. Роль бору специфічна – він є незамінним елементом живлення, без якого життєдіяльність рослин неможлива.
Serhii Prymachenko   +2 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Traumatic anterior tibiofemoral dislocation of mobile-bearing total knee arthroplasty: Two cases

open access: yesTrauma Case Reports
Background: Anterior tibiofemoral dislocation is a severe complication of a total knee arthroplasty. It is rare, and it is distinctly different from bearing spinout. Most tibiofemoral dislocations are posterior.
Carlijn Schoutens   +2 more
doaj   +1 more source

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