Results 211 to 220 of about 157,979 (290)

Long‐term benefit from adjuvant tamoxifen therapy for ER+ HER2− breast cancer by PR positivity

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Tamoxifen is a cornerstone of endocrine therapy for estrogen receptor (ER)‐positive/human epidermal growth factor receptor 2 (HER2)‐negative breast cancer. Its long‐term benefits, however, may vary by progesterone receptor (PR) status. Here, using data from the Stockholm tamoxifen trials, the authors evaluated whether PR expression predicts
Anna E. Nordenskjöld   +8 more
wiley   +1 more source

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

open access: yesiMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji   +18 more
wiley   +1 more source

"GATA3 Expression in Breast Cancers Is Strongly Associated With AR Expression in a Large TMA Study [PDF]

open access: diamond, 2017
Agedi Boto   +90 more
openalex   +1 more source

Impacts of Human Development on Wildlife Use of Corridors in Botswana 人类开发对博茨瓦纳野生动物廊道利用的影响

open access: yesIntegrative Conservation, EarlyView.
This study examined the effect of landscape‐scale human impact on wildlife in Botswana. We examined how species use wildlife corridors in two different human‐dominated landscapes. We identified differences in temporal overlap between wildlife and humans across both landscapes, which is fundamental to consider in both current and future conservation ...
Tempe S. F. Adams   +3 more
wiley   +1 more source

Domain engineered gallium oxide phototransistors enabling intelligent ultraviolet vision with dynamic gating

open access: yesInfoMat, EarlyView.
Single‐domain Si‐doped β‐Ga2O3 thin films grown on off‐axis sapphire eliminate domain boundaries, improving transport and photogating. Gate‐pulse modulation suppresses persistent photoconductivity, yielding ultrafast response and high detectivity. Integrated into a 24 × 24 array, the devices enable high frame rate DUV imaging and energy‐efficient ...
Jae Young Kim   +9 more
wiley   +1 more source

Survival in adults with high-risk TA-TMA: a comparative analysis of narsoplimab vs supportive care. [PDF]

open access: yesBlood Adv
Matsui H   +9 more
europepmc   +1 more source

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