Results 271 to 280 of about 157,979 (290)

Nanomagnetic Hyperthermia Sensitizes Gemcitabine Chemosensitivity in Pancreatic Cancer by Inhibiting HSPB1 to Amplify ACSL4‐Mediated Ferroptosis

Small, EarlyView.
ABSTRACT Pancreatic cancer, one of the most malignant solid tumors with the poorest prognosis, is commonly treated with gemcitabine (GEM)‐based systemic chemotherapy. However, chemoresistance remains a significant therapeutic challenge. Ferroptosis, a novel form of programmed cell death, has demonstrated exceptional susceptibility in chemoresistant ...
Jiaqiang Ren, Shuai Wu, Tong Su, Hugang Li, Jiachun Ding, Fan Chen, Jiantao Mo, Jie Li, Zheng Wang, Liang Han, Zheng Wu   +10 more
wiley   +1 more source

143 Ruvalizumab in the treatment of Complement-mediated Thrombotic microangiopathy (CM-TMA) Post Organ transplant

openalex   +1 more source

‘Using anuran community diversity and Pseudacris crucifer to predict landscape quality across a land use gradient'

Wildlife Biology, EarlyView.
As human‐modified landscape and climate changes proliferate, maintaining biodiversity and understanding the function and quality of available habitat is imperative. As anurans (frogs/toads) such as Pseudacris crucifer, can be an indicator species of habitat quality and ecosystem productivity, studying the anuran community in a mixed‐land use region ...
Brian C. Kron, Karen V. Root
wiley   +1 more source

Significant differences in CD276 (B7H3) expression between female and male bladder cancer tissue samples: An exploratory study. [PDF]

Curr Urol
Harland N, Reitnauer LE, Amend B, Bahlinger V, Hennenlotter J, Stenzl A, Aicher WK, Walz S.   +7 more
europepmc   +1 more source

USP44, ZNF454, and GPRC5B ctDNA Methylation Markers in Breast Cancer: Limited Clinical Relevance for Disease Monitoring and Tumor Characteristics

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We selected breast cancer‐specific DNA methylation markers using The Cancer Genome Atlas (TCGA). We analyzed the methylation and expression patterns of candidate genes in breast cancer cell lines, ctDNA, and tissue samples. The relationship between ctDNA methylation markers and the clinicopathological features of breast cancer patients was investigated.
Young Ju Jeong, Chang‐Ho Jeon, Hoon Kyu Oh, Jeong Kyu Kim, Chun‐Seok Yang, Na‐Rang Lee, Doyeon Kim   +6 more
wiley   +1 more source

STING predicts patterns of failure in locally advanced head and neck squamous cell carcinoma. [PDF]

JNCI Cancer Spectr
MacNeil T, Hayman TJ, Li S, Moutafi M, Martinez-Morilla S, Vathiotis IA, Hu R, Harari PM, Burtness B, Liu H, Kimple RJ, Rimm DL, Contessa JN.   +12 more
europepmc   +1 more source

Mediation of Polygenic Asthma Risk Through Gene Expression

Allergy, EarlyView.
We apply published PRSs in African‐ancestry individuals and quantify the extent to which the PRS‐asthma relationship is mediated by clinical biomarkers and gene‐expression signatures of asthma. We found the best PRS to be the one derived using the largest sample size and including African‐ancestry individuals.
Rakesh Natarajan, Brooke Szczesny, Kanika Kanchan, Erika Esquinca, Meher Preethi Boorgula, Sameer Chavan, Monica Campbell, Wendy Lorizio, Ayo P. Doumatey, Alvaro A. Cruz, Harold Watson, Edward T. Naureckas, B. Louise Giles, Ganiyu Arinola, Olumide Sogaolu, Adegoke G. Falade, Nadia N. Hansel, Christopher O. Olopade, Charles N. Rotimi, R. Clive Landis, Camila A. Figueiredo, Eimear E. Kenny, Ingo Ruczinski, Andrew H. Liu, Carole Ober, Margaret A. Taub, Randi K. Johnson, Kathleen C. Barnes, Genevieve L. Wojcik, Rasika A. Mathias   +29 more
wiley   +1 more source

Renal thrombotic microangiopathy impairs renal function recovery in lupus nephritis. [PDF]

Clin Kidney J
Zhang M, Zhang X, Xiang W, Yu J, Wang X, Ye H, Zhong Z, Tang R, Xia X, Chen W.   +9 more
europepmc   +1 more source

COEXIST enables rich spatial profiling of BC TMA cores.

Robert T. Heussner (21989911), Cameron F. Watson (21989914), Christopher Z. Eddy (21989917), Kunlun Wang (2794564), Eric M. Cramer (10499236), Allison L. Creason (8887589), Gordon B. Mills (6841554), Young Hwan Chang (10276110)   +7 more
openalex   +1 more source

Long‐Term Effect of Allergen Immunotherapy in Responder Local Allergic Rhinitis Patients: Symptom Control, and Prevention of Asthma and Allergic Sensitizations

Allergy, EarlyView.
LAR patients who respond to AIT during the first year and are treated for two more years continue improving (less symptoms and medication intake) during the following seven years. AIT prevents the onset of asthma and allergic sensitizations in responder LAR individuals during the seven years following discontinuation.
Almudena Testera‐Montes, Laura Zubiaga‐Fernandez, Carlos J. Aranda, Irene Garcia‐Esteban, Trinidad Ilda Gaitan‐Nievas, Dulce Sanchez‐Torralvo, Cristobalina Mayorga, Maria J. Torres, Ibon Eguiluz‐Gracia, Carmen Rondon   +9 more
wiley   +1 more source