Results 131 to 140 of about 56,141 (252)
Advanced Science, EarlyView.A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li +9 more
wiley +1 more source
Performance assessment of systems equipped with large mass tmd under seismic loading
LAUREA MAGISTRALELa prestazione sismica dei sistemi dotati di Tuned Mass Damper (TMD) di grande massa viene qui studiata eseguendo uno studio parametrico completo di un sistema idealizzato a due gradi di libertà.
Qureshi, Zarar Ali, Mehra, Ashna
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Monolayer MoS2 With Ultrahigh Piezoelectricity: From ALD Dose Control to Device Performance
Advanced Science, EarlyView.This study demonstrates that controlling precursor dosages in atomic layer deposition (ALD) serves to regulate ultrathin oxide quality, which in turn determines sulfurization behavior and MoS2 monolayer continuity. The resulting continuous, low‐defect monolayers enable improved piezoelectric performance and support a flexible slippage sensor, linking ...
Yun Li +16 more
wiley +1 more source
Advanced Science, EarlyView.We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang +19 more
wiley +1 more source
MXene‐Based Room‐Temperature NO2 Gas Sensors: A Meta‐Analysis
Advanced Science, EarlyView.This study presents the first comprehensive meta‐analysis of MXene‐based NO2 sensors, decoding 32 study characteristics across 61 peer‐reviewed studies. By isolating materials chemistry as the primary performance driver over device‐level parameters, the authors establish a methodological blueprint and a predictive structure–function map to accelerate ...
Alexander Khort +3 more
wiley +1 more source
reservedPremessa: I disturbi muscoloscheletrici del distretto cervico-cranio-mandibolare, come la cervicalgia e i disordini temporo-mandibolari (TMD), costituiscono una sfida clinica rilevante per la loro complessa eziologia multifattoriale, che ...
SALVALAJO, VALERIO
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Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
Comorbidities in a TMD patient population
, 2016 Introduction: There are numerous reports of overlap between temporomandibular disorder (TMD) and painful comorbidities, including migraines and chronic fatigue syndrome.
Dahan, Haissam
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Advanced Science, EarlyView.TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu +12 more
wiley +1 more source
Parton Shower based on TMD parton distributions
, 2019 We present a parton shower based on Transverse Momentum Dependent (TMD)parton distributions obtained with the Parton Branching method. We investigatehow well the TMD parton shower reproduces the TMD parton distributions.Applications of the TMD parton ...
Hautmann, Francesco +3 more
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