Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits
Advanced Science, EarlyView.Yeast microbes in fermenting fruits attract both host flies and their parasitoid wasps. Female Leptopilina boulardi detect yeast‐emitted ethyl esters via two olfactory receptors, LbouOR167 and LbouOR136. A conserved residue, Leu159, is critical for binding these compounds, enabling female wasps to locate host‐rich habitats.
Yueqi Lu +11 more
wiley +1 more source
Reappraisal of the Diagnostic Significance of Transcranial Magnetic Stimulation and Triple Stimulation in Amyotrophic Lateral Sclerosis. [PDF]
Eur J NeurolAndersen B, Krarup C.
europepmc +1 more source
TMS Behavior Modeling, Incentive and System Design against Piracy and Collusion
, 2007 在九年一貫教育體系與一綱多本政策下，近年來國內教材分享網站蓬勃發展。個人電腦普及與與同儕對同儕式網路讓老師能夠方便地在教材分享系統交流教材與教學經驗，教師可以增進教學能力並提供高品質教育以增進下一代孩童的競爭力。但是，目前缺少鼓勵分享行為的有效誘因。 本論文探討國小教師在台灣學術網路(TANet)上分享教材的問題，賴家將提出一混合式同儕對同儕式教材分享系統[Lai05]為基礎，其中教師為節點而教育局扮演超節點的角色。我們探討四個對教材分享系統成功但卻還沒被解決的重要議題：一、防止盜版(piracy ...
Chiou, Yi-Ren, 邱奕仁
core
Mechanozyme: An Artificial Enzyme With a Mechanophore Framework
Advanced Science, EarlyView.Mechanical destabilization of a G‐quadruplex mechanophore in a DNAzyme markedly boosts its catalytic activity, demonstrating “mechanozymes” as artificial enzymes whose functions are modulated by mechanical stress exerted by ultrasonication. This mechanozyme principle is broadly applicable to control biomolecular activities.
Jiahao Ji +7 more
wiley +1 more source
Clustering depression subgroups based on dorsolateral prefrontal-subgenual anterior cingulate cortex peak functional connectivity reveals different symptom profiles and TMS treatment outcomes. [PDF]
BMC MedKong G +13 more
europepmc +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Neurophysiological markers of GABAergic and glutamatergic function associated with childhood adversity in adolescent depression: An exploratory transcranial magnetic stimulation study. [PDF]
Prog Neuropsychopharmacol Biol PsychiatryAzamet I +5 more
europepmc +1 more source
McDiarmid HM, Douglas GR, Coomber BL, Josephy PD. 2002. 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP)‐induced mutagenesis in cultured Big BlueTM rat mammary epithelial and fibroblast cells. Environ Mol Mutagen 39:245–253. [PDF]
Environmental and Molecular Mutagenesis, 2002 openaire +1 more source
DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout
Advanced Science, EarlyView.A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li +12 more
wiley +1 more source
Advanced Science, EarlyView.The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther +13 more
wiley +1 more source