Results 31 to 40 of about 26,628 (256)

Governance inertia and forest loss in Zambia’s Game Management Areas: lessons from Greater Kafue

Academia Environmental Sciences and Sustainability
Introduction: Community-Based Natural Resource Management (CBNRM) has long been promoted in southern Africa as a participatory model for conservation, yet persistent implementation failures have been widely documented.
Simon M. Munthali, Phillip Muyoma, Masha Muguswi   +2 more
doaj   +1 more source

Neutralization potency of recombinant TNC.

, 2016
(A) Recombinant TNC was produced in 293T Lenti-X cells, purified by ammonium sulfate precipitation and HPLC. Purity was observed on a reduced SDS-PAGE gel (Coomassie stained) and a reduced Western blot (anti-TNC stained).
Tomoo Ohashi (2373616), Harold Erickson (2793220), Sallie R. Permar (161600), Robin G Mansour (2793226), Frederick Jaeger (202894), Joshua Amos (2793223), S. Munir Alam (164023), Erin McGuire (2793211), Genevieve Fouda (2793217), Kimberly Barbas (2793208), Lisa Stamper (2793214)   +10 more
core   +1 more source

Dynamics of the media corporation development in the conditions of globalization [PDF]

International Economic Policy, 2018
This article is devoted to the study of the dynamics of the media corporation development in the context of increasing globalization trends in the global economy.
Chuzhykov Andrii
doaj  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Tenascin-C predicts poor outcomes for patients with colorectal cancer and drives cancer stemness via Hedgehog signaling pathway

Cancer Cell International, 2020
Background Tenascin-C (TNC) is an extracellular matrix protein that is widely expressed in the stromal fibroblasts of various cancers. However, the roles of TNC in colorectal cancer (CRC) cells remain unclear.
Zhaoting Yang, Chengye Zhang, Ying Feng, Mingji Quan, Yan Cui, Yanhua Xuan   +5 more
doaj   +1 more source

Ca²⁺-activated isometric force of skinned porcine cardiac muscle preparations reconstituted with WT-TnC or CTV-TnC.

, 2016
(A) Endogenous TnC was extracted (solid bars) and fibers were reconstituted with either WT-TnC or CTV-TnC (gray bars). The extent of extraction and reconstitution was defined by the percent of Ca2+-activated, steady state isometric force (pCa4 ...
Myriam A. Badr (3219207), Jose R. Pinto (3219204), P. Bryant Chase (156969), Michael W. Davidson (112687)   +3 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Generation of Transgenic Mice that Conditionally Overexpress Tenascin-C

Frontiers in Immunology, 2021
Tenascin-C (TNC) is an extracellular matrix glycoprotein that is expressed during embryogenesis. It is not expressed in normal adults, but is up-regulated under pathological conditions.
Saori Yonebayashi, Kazuko Tajiri, Mari Hara, Mari Hara, Hiromitsu Saito, Noboru Suzuki, Satoshi Sakai, Taizo Kimura, Akira Sato, Akiyo Sekimoto, Satoshi Fujita, Ryuji Okamoto, Robert J. Schwartz, Toshimichi Yoshida, Toshimichi Yoshida, Kyoko Imanaka-Yoshida, Kyoko Imanaka-Yoshida   +16 more
doaj   +1 more source

RMSF of TnC N-lobe.

, 2013
A. RMSF for each residue alpha-C of TnC N-lobe (residues 5–80) measured in the core troponin complex (TnC-TnT-TnI) simulations. Ca2+ depleted observation shown in cyan, Ca2+ saturated observation shown in magenta. B.
Georgi Z. Genchev (390239), Tomoyoshi Kobayashi (390240), Hui Lu (12370)   +2 more
core   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source