Results 61 to 70 of about 26,628 (256)

TNC (tenascin C (hexabrachion))

, 2008
Review on TNC (tenascin C (hexabrachion)), with data on DNA, on the protein encoded, and where the gene is ...
Degen, M, M Degen, Chiquet-Ehrismann, R, R Chiquet-Ehrismann   +3 more
core   +1 more source

Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology

Annals of Neurology, EarlyView.
Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby, Xiaojie Liu, Melinda Wojtkiewicz, Linda Berg Luecke, Rebekah L. Gundry, Qing‐Song Liu, Allison D. Ebert   +6 more
wiley   +1 more source

Preparation of MOEAMCl and MAAm Based Hydrogels and Effective Use in Anionic Dye Adsorption

Journal of Applied Polymer Science, Volume 142, Issue 16, April 20, 2025.
ABSTRACT In this study, hydrogels based on [2‐(Methacryloyloxy)ethyl]trimethylammonium chloride (MOEAMCl) and methacrylamide (MAAm) were synthesized for the removal of anionic dyes from aqueous solutions. Following detailed characterization, the use of hydrogels for methyl orange (MO) adsorption was investigated.
Hilal Nur Duykop Demir, Ali Delibaş, Ayşe Benk, Ramazan Coşkun   +3 more
wiley   +1 more source

Ectopic expression of tnc in tubular epithelia causes excess lumen dilation.

, 2012
(A–F) The apical tracheal surface was visualized by Crb-staining in wild type embryos (A–C) and in embryos with btlGAL4-driven tnc expression (D–F, tra>tnc).
Hervé Bouhin (148559), Iris F. van Dijk-Härd (148565), Tina M. Chavoshi (148547), Sunitha Byri (148543), Zulfeqhar A. Syed (148536), Anne-Laure Bougé (148540), Erika Tång (148552), Anne Uv (148571)   +7 more
core   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

Characterization of tenascin-C as a novel biomarker for asthma: utility of tenascin-C in combination with periostin or immunoglobulin E

Allergy, Asthma & Clinical Immunology, 2018
Background Extracellular matrix proteins tenascin-C (TNC) and periostin, which were identified as T-helper cell type 2 cytokine-induced genes in human bronchial epithelial cells, accumulate in the airway basement membrane of asthmatic patients.
Mina Yasuda, Norihiro Harada, Sonoko Harada, Ayako Ishimori, Yoko Katsura, Yukinari Itoigawa, Kei Matsuno, Fumihiko Makino, Jun Ito, Junya Ono, Kazunori Tobino, Hisaya Akiba, Ryo Atsuta, Kenji Izuhara, Kazuhisa Takahashi   +14 more
doaj   +1 more source

P2X3 receptor upregulation in trigeminal ganglion neurons through TNFα production in macrophages contributes to trigeminal neuropathic pain in rats

The Journal of Headache and Pain, 2021
Background Trigeminal neuralgia is a characteristic disease that manifests as orofacial phasic or continuous severe pain triggered by innocuous orofacial stimulation; its mechanisms are not fully understood.
Momoko Koizumi, Sayaka Asano, Akihiko Furukawa, Yoshinori Hayashi, Suzuro Hitomi, Ikuko Shibuta, Katsuhiko Hayashi, Fusao Kato, Koichi Iwata, Masamichi Shinoda   +9 more
doaj   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Spatial variation and predictors of plant species' intrinsic climate sensitivity across the conterminous United States

Ecography, EarlyView.
Understanding how species' sensitivity to climate varies spatially across their ranges and elucidating the important causes is essential for identifying ecologically meaningful geographic units and conservation actions for biodiversity. In this study, we estimated climatic occurrence niches of vascular plants to explore the spatial variation in species'
Weiqing Qu, Ayla J. Skorupa, Jeffrey W. Matthews, Suneeti K. Jog, Jason T. Bried   +4 more
wiley   +1 more source

Targeting the extracellular matrix with Tenascin-C-specific CAR T cells extends survival in preclinical models of glioblastoma

Journal for ImmunoTherapy of Cancer
Background Glioblastoma (GBM) is an aggressive brain tumor associated with poor outcome and limited treatment options. Chimeric antigen receptor (CAR) T cells targeting cell surface antigens were shown to induce tumor regression in patients with GBM ...
Karl Schaller, Jana de Sostoa, Benita Wolf, Valérie Dutoit, Denis Migliorini, Stephanie Tissot, Eliana Marinari, Martin Pedard, Valérie Widmer, Suzel Davanture, Michele De Palma, Gertraud Orend   +11 more
doaj   +1 more source