Results 161 to 170 of about 1,343,714 (312)

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.

Cell, 1999
R. Chemelli, J. Willie, C. M. Sinton, J. Elmquist, T. Scammell, Charlotte E. Lee, James A. Richardson, S. Williams, Yumei Xiong, Y. Kisanuki, T. Fitch, M. Nakazato, Robert E. Hammer, C. B. Saper, M. Yanagisawa   +14 more
semanticscholar   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

Advanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua, Anira Escrichs, Yonatan Sanz Perl, Morten L. Kringelbach, Adele Diamond, Solange Denervaud, Gustavo Deco   +6 more
wiley   +1 more source

Correction: Conformal immunomodulatory hydrogels for the treatment of otitis media

Journal of Nanobiotechnology
Yuefan Jin, Yueyi Shang, Cuiping Wu, Zhengnong Chen, Haibo Shi, Hui Wang, Linpeng Li, Shankai Yin   +7 more
doaj   +1 more source

Sleep on it [PDF]

Nature Neuroscience, 2009
openaire   +2 more sources

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

To sleep or not to sleep. . .

The International Journal of Acoustics and Vibration, 2017
openaire   +1 more source

Variation in sleep duration across latitudes and countries: a Bayesian hierarchical analysis of wearable data. [PDF]

NPJ Biol Timing Sleep
Akhtar F, Brownlee A, Crawford C.
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Young and old adult brains experience opposite effects of acute sleep restriction on the functional connectivity network. [PDF]

Imaging Neurosci (Camb)
Neudorf J, Rokos L, Shen K, Kent B, McIntosh AR.   +4 more
europepmc   +1 more source