Results 81 to 90 of about 1,343,714 (312)

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Accessible moderate-to-severe obstructive sleep apnea screening tool using multidimensional obesity indicators as compact representations

iScience
Summary: Many obesity indicators have been linked to adiposity and its distribution. Utilizing a combination of multidimensional obesity indicators may yield different values to assess the risk of moderate-to-severe obstructive sleep apnea (OSA).
Xiaoyue Zhu, Chenyang Li, Xiaoting Wang, Zhipeng Yang, Yupu Liu, Lei Zhao, Xiaoman Zhang, Yu Peng, Xinyi Li, Hongliang Yi, Jian Guan, Shankai Yin, Huajun Xu   +12 more
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke, Petra Steinacker, Steffen Halbgebauer, Patrick Oeckl, Geert Mayer, Markus Otto   +5 more
wiley   +1 more source

Sleep deprivation disrupts vestibular compensation by activating TLR4/NF-κB/NLRP3 signalling in the deafferented vestibular nuclei

Brain Research Bulletin
We aimed to investigate whether sleep deprivation (SD) affects vestibular compensation and explore the underlying mechanisms. After unilateral labyrinthectomy (UL), adult mice were subjected to 6 h of SD for 5 days.
Zhuangzhuang Li, Jingwei Lai, Yini Li, Lingkang Dong, Jie Li, Tianjiao Zhou, Hangdong Shen, Huaming Zhu, Dongzhen Yu, Pengjun Wang, Haibo Shi   +10 more
doaj   +1 more source

Sleep Spindles: Mechanisms and Functions.

Physiological Reviews, 2019
Sleep spindles are burst-like signals in the electroencephalogram (EEG) of the sleeping mammalian brain and electrical surface correlates of neuronal oscillations in thalamus.
Laura M. J. Fernandez, A. Lüthi
semanticscholar   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Integrating single-cell and spatial transcriptomics reveals the cellular heterogeneity of vestibular schwannoma

npj Precision Oncology
Vestibular schwannoma (VS) is a benign tumor that can result in significant neurological and otological complications. The mechanisms underlying its development and spatial heterogeneity remain poorly understood.
Wenqi Dong, Yuchen Jin, Lingkang Dong, Yumeng Jiang, Zhuangzhuang Li, Maoxiang Xu, Jingjing Wang, Feng Liu, Dongzhen Yu   +8 more
doaj   +1 more source

Non-polar components in PM2.5 increase matrix remodeling of CRS by up-regulating CEMIP in nasal fibroblasts

Frontiers in Genetics
BackgroundFine particulate matter (PM2.5) is harmful to respiratory health and can lead to chronic rhinosinusitis (CRS). But how its components lead to CRS by affecting the function of nasal fibroblasts remains unclear.MethodsIn this study, polar organic
Jiayao Zhou, Jiayao Zhou, Jiayao Zhou, Ying Zhu, Ying Zhu, Ying Zhu, Huilin Hu, Ru Tang, Ru Tang, Ru Tang, Shiyao Zhang, Shiyao Zhang, Shiyao Zhang, Yuelong Gu, Yuelong Gu, Yuelong Gu, Song Mao, Song Mao, Song Mao, Shilei Pu, Shilei Pu, Shilei Pu, Shilei Pu, Hai Lin, Hai Lin, Hai Lin, Yue Zhao, Zhipeng Li, Zhipeng Li, Zhipeng Li, Weitian Zhang, Weitian Zhang, Weitian Zhang   +32 more
doaj   +1 more source

Problematic Internet Use in Frontotemporal Dementia: A Case Series

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The present study investigated problematic internet use (PIU) among 61 patients with frontotemporal dementia (FTD) compared to a cohort of 354 patients with mild cognitive impairment (MCI) and Alzheimer's dementia. PIU was identified in 22.9% of FTD patients compared to only 0.8% of AD patients (p < 0.001). Behaviors included compulsive social
Daniele Urso, Giuseppe Volpe, Agnese Valguarnera, Davide Vilella, Alessandra Vitulli, Valentina Gnoni, Alessia Giugno, Eleonora Rollo, Mark D. Griffiths, Giancarlo Logroscino   +9 more
wiley   +1 more source