Results 171 to 180 of about 469,006 (267)

Box–Behnken optimization and ANN‐ANFIS integrated modelling for transesterification using thermally activated basic oxygen furnace slag catalyst

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Global energy demand and environmental concerns have intensified the search for renewable and sustainable energy sources. This study thus, focuses on optimizing the transesterification process of waste cooking oil (WCO) using thermally activated basic oxygen furnace slag catalyst calcined at 850°C (BOF 850). The optimization and modelling were
Johra S. Ali, Hillary L. Rutto
wiley   +1 more source

Irregular visits in longitudinal studies: Comparing inverse intensity of visit weighting and imputation in a causal analysis of antidepressant therapeutic treatment

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Irregular observation times are common in longitudinal observational studies and can affect causal inferences. We use data from electronic health records of Kaiser Permanente Washington patients in the United States who initiated an antidepressant medication between 2008 and 2018, with a confirming diagnosis of depression. We are interested in
Janie Coulombe   +2 more
wiley   +1 more source

Community Head and Neck Cancer Knowledge, Engagement, Research, and Screening (CHECKERS): Protocol for a Community‐Engaged Approach to Head and Neck Cancer Prevention

open access: yesCancer Nexus, EarlyView.
ABSTRACT Introduction Unequal access to care is associated with disparities in prevention, early detection, and outcomes of head and neck cancer (HNC), especially in underserved populations. Community‐engaged research (CEnR) aims to build capacity for community members to address health inequity via bidirectional partnerships with healthcare ...
Nicholas A. Frisco   +11 more
wiley   +1 more source

Intelligent Automation Improved Efficiency in Pharmacovigilance Safety Signal Assessment

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pharmacovigilance is the science involving the detection, assessment, understanding, and prevention of adverse events associated with drugs, biologics, or medical devices. In pharmacovigilance, information that suggests a new potential causal relationship between an intervention and an adverse event is called a safety signal. Following their detection,
Jeffrey Warner   +3 more
wiley   +1 more source

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke   +12 more
wiley   +1 more source

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy