Results 41 to 50 of about 338,544 (255)
, 2008 The assessment describes the current status of tobacco control efforts in Kenya, what information is readily available in terms of published literature, the infrastructure already existing for tobacco control, and a SWOT analysis (Strengths, Weaknesses ...
Kenya Tobacco Control Situational Analysis Consortium
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Review of tobacco control services [PDF]
, 2014 In New Zealand, tobacco use is the single largest cause of preventable death, and a major factor contributing to health inequality. Half of all long-term smokers die from a smoking-related illness and the average lifespan of long-term smokers who die ...
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Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Advanced Science, EarlyView.Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
, 2014 The conference provided an opportunity for Asian participants to gain a better understanding of effective population-wide interventions to prevent non-communicable diseases (NCDs).
Global Tobacco Control Forum
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Advanced Science, EarlyView.TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang +18 more
wiley +1 more source
Advanced Science, EarlyView.In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang +15 more
wiley +1 more source
, 2010 The table of contents for this item can be shared with the requester. The requester may then choose one chapter, up to 10% of the item, as per the Fair Dealing provision of the Canadian Copyright ActTobacco Production is labour intensive, leading to use ...
Kenya Tobacco Control Situational Analysis Consortium
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Advanced Science, EarlyView.Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li +13 more
wiley +1 more source
, 2010 This paper identifies and discusses the legal framework (international and national) related to Tobacco Advertising, Promotion and Sponsorship (TAPS). It analyses the implementation of the laws governing TAPS and identifies the TAPS strategies used by ...
Kenya Tobacco Control Situational Analysis Consortium
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The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos
Advanced Science, EarlyView.Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan +8 more
wiley +1 more source