Results 251 to 260 of about 120,321 (332)

Prognostic Value of the C‐PLAN Index in Advanced Esophageal Squamous Cell Carcinoma Patients Treated With Immune Checkpoint Inhibitors

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study evaluated the prognostic value of the C‐PLAN index in advanced esophageal squamous cell carcinoma (ESCC) patients receiving immune checkpoint inhibitor (ICI) therapy. A retrospective analysis of 241 eligible patients treated during February 2020 to January 2023 was conducted.
Yi Zhou   +5 more
wiley   +1 more source

[What does Harm Reduction in Tobacco Use means to Public Health]. [PDF]

open access: green
Javier Ayesta   +9 more
openalex  

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan   +9 more
wiley   +1 more source

Adolescence risk factors for meniscus and ligamentous knee injuries in adulthood: A longitudinal study

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Our aim is to investigate the influence of adolescent health‐related behaviours on the occurrence of meniscus and ligament injuries in a large cohort of Finnish adolescents with an average 27‐year follow‐up. Methods The baseline data were surveys conducted biannually from 1981 to 1997, and these were individually linked to outcomes, as
Matias Vaajala   +6 more
wiley   +1 more source

A standardized surgical technique for DAIR improves treatment success rates in acute periprosthetic knee infection

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Results after debridement, antibiotics and implant retention (DAIR) for acute periprosthetic knee joint infections (PJIs) vary widely. Although data are limited, surgeon expertise and surgical technique likely influence outcomes. Standardized DAIR performed by surgeons within a multidisciplinary team (MDT) dedicated to the treatment of
Guillermo Sánchez‐Rosenberg   +4 more
wiley   +1 more source

GERD and Upper Aerodigestive Tract Cancer Risk: A Systematic Review and Meta‐Analysis

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective Gastroesophageal reflux disease (GERD) is highly prevalent, yet its association with upper aerodigestive tract (UADT) cancers beyond esophageal adenocarcinoma remains incompletely defined. This systematic review and meta‐analysis aimed to quantify the risk of specific UADT cancers in individuals with GERD.
Janice Huang   +10 more
wiley   +1 more source

The Genomic Evolution of Early‐Stage Non‐Small Cell Lung Cancer

open access: yesMedicine Advances, EarlyView.
This study provides a comprehensive overview of the genomic landscape of early‐stage non‐small cell lung cancer, identifying the 4q12 deletion as a potential exclusive biomarker for the “oncogenic switch” from pre‐invasive to invasive lesions. It delineates that while EGFR and TP53 mutations act as early truncal drivers, the progressive increase in ...
Huatao Tang, Yang Zhang, Haiquan Chen
wiley   +1 more source

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