Results 21 to 30 of about 24,498 (209)

Toward pharmacy-based smoking cessation services in Nigeria: Knowledge, perception and practice of community pharmacists

Population Medicine, 2021
Introduction Worldwide, tobacco smoking is one of the leading causes of avoidable deaths. In Nigeria, there is currently no clinical guidelines for tobacco dependence treatment.
Wuraola Akande-Sholabi, Yusuff Adebayo Adebisi   +1 more
doaj   +1 more source

Vaping: Scientific manipulation in Spain

Tobacco Prevention and Cessation, 2023
Introduction Tobacco industry is betting on vaping and heated tobacco to maintain the bottom line. They use the same tactics used with cigarettes: advertising to minors, fierce opposition to regulations and scientific manipulation.
Rodrigo Cordoba-Garcia, Vidal Barchilon-Cohen   +1 more
doaj   +1 more source

Compound enzyme and low-oxygen co-fermentation improves aroma quality and reduces irritation of cigar tobacco leaves

Industrial Crops and Products
Combined use of compound enzymes and low-oxygen conditions is a promising approach for tobacco fermentation. Nevertheless, the regulatory mechanism of this co-fermentation system on flavor formation in cigar tobacco leaves remains unclear. This work aims
Wei Liu, Mengru Bai, Yanqing Qin, Tian Zhou, Qiu Zhong, Jun Wang, Yuanyuan Zhao, Hongzhi Shi   +7 more
doaj   +1 more source

Mechanisms for reducing cigar tobacco leaf irritancy during acidic fermentation

AMB Express
This study explored the effects of an acidic fermentation environment on the quality of cigar tobacco leaves using air-cured “Dexue 1” tobacco leaves as the raw material.
Wei Liu, Yuanyuan Zhao, Tian Zhou, Mengru Bai, Jun Wang, Caining Qi, Jiayi Li, Yanqing Qin, Hongzhi Shi   +8 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

How does (public health) ethics address “harm reduction”?

Tobacco Prevention and Cessation, 2019
Introduction Tobacco related diseases and its global control is among prior issues of public health science. Recent threats also known as “new” products including e-cigarette, heated tobacco products, etc raise also “new” questions to be answered ...
Dilek Aslan
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Effects of green manuring on chemical characteristics and microecology of tobacco-growing soil in central henan

BMC Microbiology
Objective This study explored green manuring effects on microecology, carbon/nitrogen levels, and enzyme activity in tobacco-growing soils. Methods After 30,000 kg·hm⁻² overpressure and 28 days of natural decomposition, plants (Hordeum vulgare L.
Wei Liu, Xiaolong Chen, Yuanyuan Zhao, Hongzhi Shi   +3 more
doaj   +1 more source