Results 61 to 70 of about 84,630 (297)

How does (public health) ethics address “harm reduction”?

Tobacco Prevention and Cessation, 2019
Introduction Tobacco related diseases and its global control is among prior issues of public health science. Recent threats also known as “new” products including e-cigarette, heated tobacco products, etc raise also “new” questions to be answered ...
Dilek Aslan
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Effects of green manuring on chemical characteristics and microecology of tobacco-growing soil in central henan

BMC Microbiology
Objective This study explored green manuring effects on microecology, carbon/nitrogen levels, and enzyme activity in tobacco-growing soils. Methods After 30,000 kg·hm⁻² overpressure and 28 days of natural decomposition, plants (Hordeum vulgare L.
Wei Liu, Xiaolong Chen, Yuanyuan Zhao, Hongzhi Shi   +3 more
doaj   +1 more source

Do Tobacco Companies Have an Incentive to Promote “Harm Reduction” Products?: The Role of Competition

Nicotine & Tobacco Research, 2023
Introduction Some cigarette companies have started to talk about replacing cigarettes with less harmful alternatives, which might include nicotine vaping products (NVPs), heated tobacco products (HTPs), and oral nicotine delivery products.
D. Levy, F. Thirlway, D. Sweanor, Alex C Liber, L. M. Sánchez-Romero, R. Meza, C. Douglas, K. Cummings   +7 more
semanticscholar   +1 more source

Co-optation of harm reduction by Big Tobacco [PDF]

Tobacco Control, 2020
Harm reduction is a respected public health strategy for managing addictive behaviours that pose severe health risks. Such an approach recognises that for people unable to abstain from a certain risky behaviour, public health interventions can be used to mitigate the potential dangers and health risks.
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Can the use of smokeless tobacco products be Accepted as a harm reduction method in tobacco Addiction?

, 2014
0The goal of smoking cessation treatment is to keep the patient completely away from tobacco and tobacco products. The aim of harm reduction strategies in tobacco control is to reduce the risks associated with tobacco use.
Küçük, Çağla Uyanusta, AYTEMUR, ZEYNEP AYFER, Elbek, Osman, Akçay, Şule, KILINÇ, OĞUZ, ÖZTUNA, FUNDA, Dağlı, Elif   +6 more
core   +3 more sources

Tobacco Harm Reduction and Nicotine Containing Products: Research Priorities and Policy Directions [PDF]

, 2013
Developments in tobacco harm reduction (HR) and the proliferation of nicotine containing products (NCPs) have important implications for tobaco control (TC).
Hastings, Gerard, De Andrade, Marisa
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