Results 241 to 250 of about 3,526,344 (317)

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu   +15 more
wiley   +1 more source

Applications of nanocarrier‐delivered RNA interference in agricultural biological control (2009–2025)

open access: yesNew Plant Protection, EarlyView.
Despite 17 years of development, the effectiveness of nanocarrier‐delivered RNAi pesticide (NDRP) for agricultural biological control remains limited. The successful development of effective NDRP development requires the coordinated optimization of target gene selection and nanocarrier properties, including RNA dosage, multi‐gene targeting, protection ...
Shi Dong Wang   +4 more
wiley   +1 more source

Alternative Crops for the European Tobacco Industry: A Systematic Review. [PDF]

open access: yesPlants (Basel)
Mavroeidis A   +5 more
europepmc   +1 more source

Primary and Secondary Implantation in Mandibular Reconstruction: A Systematic Review and Meta‐analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To identify clinical factors influencing implant placement/timing decisions, through comparing survival, success, and complication rates of primary and secondary dental implantation following mandibular reconstruction. Data Sources A systematic search was conducted in the PubMed, Embase, and Cochrane Central Register of Controlled ...
Laura Zsófia Tasi   +10 more
wiley   +1 more source

2‐Amino‐3H‐phenoxazin‐3‐one is a lead inhibitor of Cuscuta campestris early development: structure–activity relationships of o‐aminophenol‐derived allelochemicals

open access: yesPest Management Science, EarlyView.
Phenoxazinones caused differential types of phytotoxic effects in C. campestris early development. APO is a coherent lead inhibiting C. campestris germination and early seedling growth. Abstract BACKGROUND 2‐Amino‐3H‐phenoxazin‐3‐one (synonym: questiomycin A; abbreviated as APO or Phx‐3) is a naturally occurring phenoxazinone‐type allelochemical with ...
Cristina Díaz‐Franco   +5 more
wiley   +1 more source

Host‐induced silencing of the Minc09294 effector gene impairs Meloidogyne incognita and M. Enterolobii infection

open access: yesPest Management Science, EarlyView.
Host‐induced gene silencing of the effector candidate Minc09294 significantly impairs Meloidogyne incognita parasitism, markedly reducing gall formation, reproduction, and the development of specialized giant cells, with partial cross‐species effects on M.
João Pedro Abreu‐Sousa   +16 more
wiley   +1 more source

Correction: Hyperspectral estimation of magnesium content in Yunyan 87 and Zhongyan 100 tobacco leaves using machine learning

open access: yesFrontiers in Plant Science
Beibei Li   +5 more
doaj   +1 more source

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