Results 31 to 40 of about 3,526,344 (317)

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Isothermal Drying Characteristics and Kinetic Mechanism for Tobacco with Different Water Content

open access: yesBioResources, 2023
The effect of drying temperature on the drying characteristics of tobacco was investigated with different water content. The isothermal drying characteristics and kinetics of three kinds of tobacco on the production line of a tobacco factory in Hubei ...
Wenfeng Liu   +7 more
doaj   +2 more sources

The Tobacco Industry and Children’s Rights [PDF]

open access: yesPediatrics, 2018
The manufacture, use, and marketing of tobacco present a serious threat to children’s right to health. This makes the Convention on the Rights of the Child a potentially powerful tobacco-control tool and the United Nations Children’s Fund (UNICEF), which oversees the convention’s implementation, a potential leader in tobacco control.
van der Eijk, Yvette   +2 more
openaire   +4 more sources

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the treatment effect of anticoagulation versus antiplatelet therapy in patients ...
Elena Badillo Goicoechea   +53 more
wiley   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki   +6 more
wiley   +1 more source

Degradation and mechanism analysis of protein macromolecules by functional bacteria in tobacco leaves

open access: yesFrontiers in Microbiology
Tobacco, a crop of significant economic importance, was greatly influenced in leaf quality by protein content. However, current processing parameters fail to adequately meet the requirements for protein degradation.
Chuandong Jiang   +13 more
doaj   +1 more source

The Tobacco Industry [PDF]

open access: yesScientific American, 1901
n ...
openaire   +1 more source

Analysis of media reports to understand tobacco industry tactics in undermining tobacco tax policies in Bangladesh

open access: yes, 2018
Background Mass media plays an important role in influencing tobacco control policies. The tobacco industry also uses the mass media to promote their products and undermine tobacco control policies, in particular tobacco tax policies.
Sushanta Kumar Singha
core   +1 more source

The case for OFSMOKE: how tobacco price regulation is needed to promote the health of markets, government revenue and the public. [PDF]

open access: yes, 2010
Mainstream economic theory outlines four main causes of market failure and it is already well established that two of these (information failure and externalities) exist in a tobacco market.
Gilmore, Anna B   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy