Results 21 to 30 of about 121,345 (281)

Smoking prevalence among adults in households with children: parental survey

open access: yesMedičnì Perspektivi, 2023
The effects of tobacco smoke and nicotine on the health of adults and children remain one of the most burning problem in our days. In 2019 the prevalence of active smoking in Ukraine reached 42.0 among men and 14.4% among women.
O.O. Starets, D.A. Kovalenko
doaj   +1 more source

Effects of repeated cigarette smoke extract exposure over one month on human bronchial epithelial organotypic culture

open access: yesToxicology Reports, 2018
Cigarette smoke is a known risk factor for inflammatory diseases in the respiratory tract, and inflammatory exacerbation is considered pivotal to the pathogenesis of these diseases.
Shigeaki Ito   +2 more
doaj   +1 more source

Gendered factors for heated tobacco product use: Focus group interviews with Korean adults

open access: yesTobacco Induced Diseases, 2020
Introduction Since June 2017, heated tobacco products (HTPs) have been on sale in Korea, comprising approximately 11.8% of total tobacco sales in April 2019.
Kwanwook Kim, Jinyoung Kim, Hong-Jun Cho
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Proof of concept for quantitative adverse outcome pathway modeling of chronic toxicity in repeated exposure

open access: yesScientific Reports
Adverse Outcome Pathway (AOP) is a useful tool to glean mode of action (MOE) of a chemical. However, in order to use it for the purpose of risk assessment, an AOP needs to be quantified using in vitro or in vivo data.
Shigeaki Ito   +8 more
doaj   +1 more source

Purchase Intent and Product Appeal of Velo Nicotine Pouches Among Current Tobacco Users and Nonusers of Tobacco

open access: yesContributions to Tobacco and Nicotine Research, 2023
Oral nicotine pouches is a rapidly growing product category that potentially offers less risk than combustible tobacco products. Nicotine pouches may provide harm reduction for smokers because they contain no tobacco and have reduced harmful constituents
Freeland Robert E.   +5 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Exploring the role of oxidative stress and mitochondrial dysfunction in β-damascone-induced aneuploidy

open access: yesGenes and Environment
Background The rose ketone β-damascone (β-Dam) elicits positive results in the in vitro micronucleus (MN) assay using human lymphocytes, but shows negative outcomes in the Ames test and combined in vivo MN and comet assays.
Tsuneo Hashizume   +3 more
doaj   +1 more source

Tobacco companies are booming despite an economic depression

open access: yesTobacco Induced Diseases, 2009
During the past year, an economic crisis has affected economies and life styles throughout the world. However, the three largest transnational tobacco companies – Philip Morris International, British American Tobacco, and Japan Tobacco – showed excellent
Peisen He, Eiji Yano
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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