Results 91 to 100 of about 20,191 (199)

Targeting progressive multiple sclerosis: Toward mechanism‐informed precision medicine

Journal of Internal Medicine, Volume 300, Issue 3, Page 238-257, September 2026.
Abstract Multiple sclerosis has undergone a therapeutic revolution over the past three decades. Randomized clinical trials and real‐world data demonstrate that modern disease‐modifying therapies substantially reduce relapse rates and acute inflammatory activity detected by magnetic resonance imaging (MRI).
Fredrik Piehl, Gonçalo Castelo‐Branco, Maja Jagodic, Tomas Olsson   +3 more
wiley   +1 more source

Effects of passive inhalation of cigarette smoke on structural and functional parameters in the respiratory system of guinea pigs

Jornal Brasileiro de Pneumologia
Objective: To evaluate the effects of passive inhalation of cigarette smoke on the respiratory system of guinea pigs. Methods: Male guinea pigs were divided into two groups: control and passive smoking, the latter being exposed to the smoke of ten ...
Thiago Brasileiro de Vasconcelos, Fernanda Yvelize Ramos de Araújo, João Paulo Melo de Pinho, Pedro Marcos Gomes Soares, Vasco Pinheiro Diógenes Bastos   +4 more
doaj   +1 more source

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 313-323, August 2026.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source

The Effects of High‐ and Moderate‐Intensity Exercise on Epithelial Integrity Markers and Inflammatory Responses in Healthy Young Men

European Journal of Sport Science, Volume 26, Issue 8, August 2026.
ABSTRACT The effects of exercise intensity on airway epithelial integrity markers and inflammatory responses remain unknown. Therefore, we investigated the effects of high‐ and moderate‐intensity exercise on airway epithelial integrity markers (club cell protein 16 [CC16], surfactant protein D [SP‐D], and the CC16/SP‐D ratio), along with systemic ...
Saeid Nikoukheslat, Hadi Pourmanaf, Vahid Sari‐Sarraf, Ramin Amirsasan, Dean E. Mills   +4 more
wiley   +1 more source

Malignant Transformation of Oral Epithelial Dysplasia in Southern Finland

Head &Neck, Volume 48, Issue 8, Page 2231-2237, August 2026.
ABSTRACT Background Oral epithelial dysplasia (OED) often precedes oral squamous cell carcinoma (OSCC). The aim was to elucidate the risk and time of malignant transformation (MT) of OED. Methods Patients diagnosed with OED between 2001 and 2011 in Helsinki and Uusimaa, Finland were included.
Katariina Leino, Hanna K. Laine, Ville Kinnula, Jaana Rautava   +3 more
wiley   +1 more source

Chronic Diseases and Health Related Quality of Life in South and Southeast Asia: A Systematic Review of Burden, Interventions, and Measurement Tools

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background In South and Southeast Asia, chronic diseases (CD) are a major public health concern and have a considerable impact on people's quality of life (QoL). CD and their ailments place a dual burden of sickness and socioeconomic difficulties on afflicted people and healthcare systems.
Fardina Rahman Omi, Farhana Zaman, S.M. Saidur Rahman Mashreky   +2 more
wiley   +1 more source

Air pollution vs. tobacco smoking

European Heart Journal, 2019
Philippe Girard, Thibault Vieira
openaire   +2 more sources

Ischemic Heart Disease in the Middle East and North Africa, 1990–2021: An Integrated Analysis of Temporal Trends, Country‐Level Variation, SDI Patterns, and Risk Factors

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Ischemic heart disease (IHD) remains a leading cause of mortality and disability worldwide. Using Global Burden of Disease (GBD) 2021 estimates, this study provides an integrated assessment of IHD burden across the Middle East and North Africa (MENA) region from 1990 to 2021, highlighting temporal trends, inter‐country heterogeneity,
Nahid Karamzad, Saeid Safiri, Amir Ghaffari Jolfayi, Seyed Ehsan Mousavi, Fatemeh Amiri, Mohammad Rahmanian, Mark J. M. Sullman, Ali‐Asghar Kolahi   +7 more
wiley   +1 more source

Pre and postnatal effect of maternal environmental tobacco smoke exposure on infant's growth parameters

Journal of the Pakistan Medical Association
Objective: To determine the association between environmental tobacco smoke exposure and growth parameters of infants. Method: The observational, comparative study was done in rural areas of the Al-Karkh sector of Baghdad, Iraq, from December 2021 to
Nada Ziyad Salim, Ban Sahib Diab
doaj   +1 more source

Gender Differences in Knowledge, Perceptions, and Practices Related to Pesticide Use Among Vegetable Farmers in the Hills of Nepal: A Mixed‐Methods Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Overuse and misuse of chemical pesticides remain a major threat to public health in agricultural communities of the least developed and low‐income countries. Gender‐based differences in agricultural settings, access to agricultural information, and decision‐making play a crucial role in influencing farmers' knowledge ...
Govinda Bhandari, Sunil Ghimire, Mandira Sapkota   +2 more
wiley   +1 more source