Results 91 to 100 of about 59,165,317 (350)

Psychological Risk Factors for Alcohol, Cannabis, and Various Tobacco Use among Young Adults: A Longitudinal Analysis

Substance Use & Misuse, 2019
Background: Alcohol, cannabis, and tobacco use are prevalent in young adults and may be differentially related to psychological symptoms characterized as externalizing or internalizing.
J. Bierhoff, R. Haardörfer, M. Windle, C. Berg   +3 more
semanticscholar   +1 more source

The Maize ZmbHLH118 Transcription Factor Regulates Vacuolar Nitrate Loading by the NO3− Transporter ZmCLCa

Advanced Science, EarlyView.
In maize, the bHLH transcription factor ZmbHLH118 directly binds to the promoter of ZmCLCa and inhibits its expression. Tonoplast‐localized ZmCLCa mediates NO3− influx into the vacuole to regulate intracellular NO3− homeostasis, modulating nitrate uptake and metabolism, plant growth, and grain yield.
Chaonan Zhang, Elsa Demes‐Causse, Xujian Li, Zhenhui Guo, Hanshu Zhao, Huairong Cao, Yajing Song, Lijun Mu, Kaikai Zhang, Jing Zhang, Zhongtao Jia, Lixing Yuan, Alexis De Angeli, Jingbo Zhang   +13 more
wiley   +1 more source

A stakeholder-driven approach to designing a peer recovery coach role for implementation in community-oriented primary care teams in South Africa

Addiction Science & Clinical Practice
Introduction In South Africa, community-oriented primary care teams work to re-engage out-of-care people with HIV (PWH) in treatment, many of whom have substance use (SU) concerns.
Bronwyn Myers, Kristen S. Regenauer, Kim Johnson, Imani Brown, Alexandra L. Rose, Nonceba Ciya, Sibabalwe Ndamase, Yuche Jacobs, Morgan S. Anvari, Abigail Hines, Dwayne Dean, Rithika Baskar, Jessica F. Magidson   +12 more
doaj   +1 more source

The Impacts of Supervised Exercise Intervention on Tobacco Withdrawal Symptoms

Tobacco Use Insights, 2023
This study examined a supervised moderate-intensity aerobic exercise programme’s effectiveness in regulating the Tobacco Withdrawal Symptoms (TWS) during temporary abstinence. This was a single group, pre and post-quasi intervention study.
Nur-Hasanah Ruslan, Siti Munira Yasin, Nadzimah Mohd Nasir, Mohamad Rodi Isa   +3 more
doaj   +1 more source

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. [PDF]

, 2019
Tobacco and alcohol use are leading causes of mortality that influence risk for many complex diseases and disorders1. They are heritable2,3 and etiologically related4,5 behaviors that have been resistant to gene discovery efforts6-11.
23andMe Research Team, Bjornsdottir, Gyda, Boardman, Jason D, Boehnke, Michael, Boomsma, Dorret I, Brazel, David M, Chen, Chu, Chen, Fang, Choquet, Hélène, Cucca, Francesco, Datta, Gargi, Davies, Gareth E, Davila-Velderrain, Jose, Docherty, Anna R, Eaton, Charles B, Ehringer, Marissa A, Esko, Tõnu, Faul, Jessica D, Fiorillo, Edoardo, Foerster, Johanna R, Fritsche, Lars G, Gabrielsen, Maiken Elvestad, Gillespie, Nathan A, Gordon, Scott D, Gudbjartsson, Daniel F, Haessler, Jeffrey, Haller, Toomas, Harris, Kathleen Mullan, Heath, Andrew C, Hewitt, John K, Hickie, Ian B, Hokanson, John E, Hopfer, Christian J, Hottenga, Jouke-Jan, Huang, Hongyan, HUNT All-In Psychiatry, Hunter, David J, Iacono, William G, Jang, Seon-Kyeong, Jansen, Philip R, Jiang, Yu, Johnson, Eric O, Kamatani, Yoichiro, Kardia, Sharon LR, Keller, Matthew C, Kellis, Manolis, Kooperberg, Charles, Kraft, Peter, Krauter, Kenneth S, Laakso, Markku, Li, Yue, Lind, Penelope A, Ling, Yueh, Liu, Mengzhen, Loukola, Anu, Lutz, Sharon M, Madden, Pamela AF, Martin, Nicholas G, Matoba, Nana, McGue, Matt, McGuire, Daniel, McMahon, George, McQueen, Matthew B, Medland, Sarah E, Metspalu, Andres, Mohlke, Karen L, Mulas, Antonella, Mägi, Reedik, Nielsen, Jonas B, Okada, Yukinori, Orrù, Valeria, Palviainen, Teemu, Pandit, Anita, Peters, Ulrike, Polderman, Tinca JC, Posthuma, Danielle, Reginsson, Gunnar W, Reiner, Alexander P, Rice, John P, Rimm, Eric, Rose, Richard J, Runarsdottir, Valgerdur, Skogholt, Anne Heidi, Smith, Jennifer A, Stallings, Michael C, Stančáková, Alena, Stefansson, Hreinn, Taylor, Amy E, Thai, Khanh K, Tian, Chao, Tindle, Hilary A, Turman, Constance, Wedow, Robbee, Willemsen, Gonneke, Young, Hannah, Young, Kendra A, Zajac, Gregory JM, Zhan, Xiaowei, Zhao, Wei, Zhou, Wei   +99 more
core  

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

Patient and provider perceptions of the relationship between alcohol use and TB and readiness for treatment: a qualitative study in South Africa

BMC Public Health
Background Unhealthy alcohol use is widespread in South Africa and has been linked to tuberculosis (TB) disease and poor treatment outcomes. This study used qualitative methods to explore the relationship between TB and alcohol use during TB treatment ...
Suchitra Kulkarni, Sarah E. Weber, Chané Buys, Tersius Lambrechts, Bronwyn Myers, Mari-Lynn Drainoni, Karen R. Jacobson, Danie Theron, Tara Carney   +8 more
doaj   +1 more source

Smoking cessation [PDF]

"Treating Tobacco Use and Dependence: 2008 Update, a Public Health Service- sponsored Clinical Practice Guideline, is a product of the Tobacco Use and Dependence Guideline Panel ("the Panel"), consortium representatives, consultants, and staff.
United States Tobacco Use and Dependence Guideline Panel.
core  

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

Advanced Science, EarlyView.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng, Shaochen Jia, Fei Cao, Cuiping Liu, Heshuang Zhang, Gang Xu, Jixin Zhuang, Yashi Zhang, Can Liu, Yuhang Zhao, Zilin Guo, Xinjie Yuan, Jiaqing Yang, Lei Chu, Bowei Cai, Hu Zhao, Chao Yang   +16 more
wiley   +1 more source

Developing a standardised global survey to monitor alcohol use and related harms among school-going adolescents

Discover Public Health
Harmful alcohol use is a leading contributor to adolescent morbidity and mortality worldwide, linked to injuries, risky sexual behaviors, and long-term disease.
Cosmas Zyambo, Wingston Felix Ng’ambi
doaj   +1 more source