Results 161 to 170 of about 1,067,716 (304)

Joint modeling of alcohol and tobacco use among adults in Uganda. [PDF]

PLoS One
Kakaire G, Chumoh EC.
europepmc   +1 more source

Impacts of the Fair and Equitable Tobacco Reform Act of 2004 on Shareholders’ Wealth in the Tobacco Industry [PDF]

This study examines the impact and efficiency of the design of the Fair and Equitable Tobacco Reform Act of 2004 in deregulating the tobacco production industry.
Carver, Brian C., Feleke, Shiferaw T., Tiller, Kelly   +2 more
core   +1 more source

Mechanism‐informed machine learning for individualized tacrolimus dose adjustment in the early post‐kidney transplant period

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus dosing in the early post‐kidney transplant period is challenging due to a narrow therapeutic index and substantial interindividual pharmacokinetic (PK) variability. This study aimed to develop and validate mechanism‐informed machine learning (ML) models to support individualized tacrolimus dosing during this critical period ...
Hui Yu, Zihan Qin, Logan S. Smith, Jeong M. Park, Hao‐Jie Zhu   +4 more
wiley   +1 more source

The interaction of tobacco retailer density and rurality with tobacco use prevalence in Kentucky. [PDF]

J Rural Health
Rose SW, Christian WJ, Venne JV, Mattingly D, Fennell BS, Feizy S, Rayens MK.   +6 more
europepmc   +1 more source

Community pharmacists' practices and perspectives on deprescribing high‐risk psychotropic medicines: National survey findings

British Journal of Clinical Pharmacology, EarlyView.
Aim To explore the practices, confidence and perspectives of community pharmacists in deprescribing high‐risk psychotropic medicines, including opioid analgesics, benzodiazepine, gabapentinoids and medicinal cannabis. Methods An anonymous, cross‐sectional national online survey was conducted between January and April 2025 among Australian community ...
Monica Jung, Louisa Picco, Aili V. Langford, Rose Laing, Jana Dostal, Suzanne Nielsen   +5 more
wiley   +1 more source

Associations of cannabis, alcohol, and tobacco use combinations with sleep health. [PDF]

Addict Behav Rep
Reichenberger DA, Hebl J, Shea SA, Bowles NP.   +3 more
europepmc   +1 more source

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang, Jennifer A. Winton, Kyle T. Matschke, Alexandre Stouffs, Kimberly C. Lee, Yuanyuan Zhang, Wenlian Qiao, Weiwei Tan   +7 more
wiley   +1 more source

Economy-wide impact of a reduction in tobacco use in India. [PDF]

Tob Control
John RM, Narayanan B, Chakravarthy S, Bharathi S, Sinha P, Munish VG, Goodchild M.   +6 more
europepmc   +1 more source

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh, Kate Hanrott, Olof Breuer, Johan Bylund, Björn Schultze, Virginia Norris   +5 more
wiley   +1 more source

Effects of Tobacco Use on Oral Cancer Screening Algorithm Performance. [PDF]

Cancers (Basel)
Kanagandram E, Alp A, Takesh T, Wink C, Yang S, Davis A, Hurlbutt M, Block J, Wilder-Smith P.   +8 more
europepmc   +1 more source