Results 131 to 140 of about 203,459 (318)

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

Comparative Effect of African Walnut Oil and Docosahexaenoic Acid on, Cancer Antigen C15‐3, Biochemical and Histopathological Markers of Female Wistar Rats With 7,12‐Dimethylbenz[a]anthracene‐Induced Breast Cancer

Cancer Nexus, EarlyView.
ABSTRACT This work compares the effect of African walnut oil and docosahexaenoic acid (DHA) on cancer antigen C15‐3 (CA15‐3), biochemical, and histopathological markers of rats with 7,12‐dimethylbenz[a]anthracene‐induced (DMBA) breast cancer. 18 rats with tumor were randomized into three groups of six rats each: The negative control, the positive ...
Fabrice Tonfack Djikeng, Brenda Sandrine Tiadjo, Eurydice Flore Tiepma Ngongang, Hilaire Macaire Womeni   +3 more
wiley   +1 more source

Contexts enhance ratings of craving and psychophysiological responses of cue-reactivity in tobacco use disorder [PDF]

, 2022
Sabine Vollstädt‐Klein, Frauke Nees, Alfred Wieland, Damian Karl, Carsten Diener, Michael N. Smolka, Herta Flor   +6 more
openalex   +1 more source

A Phase 1 Open‐Label Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single Intranasal Dose of Zavegepant in Healthy Chinese Adults

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Zavegepant is the only calcitonin gene‐related peptide antagonist approved as a nasal spray in the United States for acute treatment of migraine in adults with or without aura. This Phase 1, open‐label study evaluated the pharmacokinetics, safety, and tolerability of a single intranasal dose of zavegepant 10 mg in 12 healthy Chinese adults ...
Qiong Wei, Jufang Wu, Yangyi Dai, Jiaye Lin, Beikang Ge, Yanhui Sun, Jing Zhang, Jing Wang, Chen Li, Ding Ding, Jing Liu, Mohamed H. Shahin   +11 more
wiley   +1 more source

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye, Rui Zhang, Jing Wan, Jinping Zhou, Pengpeng Guo, Dianwen Yu, Peixia Li, Yani Liu, Shaojun Shi   +8 more
wiley   +1 more source

Effects of High‐ and Low‐Fat Meals on the Bioavailability and Pharmacokinetics of Votoplam, a HTT Gene Splicing Modifier

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee, Amy‐Lee Richards, Nageswara Reddy, Brian Beers, Lee Golden, Ronald Kong   +5 more
wiley   +1 more source

The Associations Between Vegetarian and Vegan Diets and Orthorexia Nervosa Symptoms in Adults: A Systematic Review and Meta‐Analysis

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To synthesize the evidence on the associations between vegetarian and/or vegan diets (VVDs) and symptoms of orthorexia nervosa (ON) compared with omnivorous diets in the adult population. Method Following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) and the Meta‐analyses of Observational Studies in ...
Valentina Díaz‐Goñi, Bruno Bizzozero‐Peroni, María Eugenia Visier‐Alfonso, Estela Jiménez‐López, Rubén Fernández‐Rodríguez, José Francisco López‐Gil, Tomás Olivo Martins‐de‐Passos, Alberto Durán González, Vicente Martínez‐Vizcaíno, Arthur Eumann Mesas   +9 more
wiley   +1 more source

Relationship of serum prolactin with severity of drug use and treatment outcome in cocaine dependence. [PDF]

, 2004
RATIONALE: Alteration in serum prolactin (PRL) levels may reflect changes in central dopamine activity, which modulates the behavioral effects of cocaine.
Berrettini, Wade H., Certa, Kenneth M., Mannelli, Paolo, Murray, Heather, Patkar, Ashwin A., Peindl, Kathleen, Vergare, Michael J.   +6 more
core   +1 more source

Informed Choice in the Context of Tobacco Use Disorder [PDF]

Nicotine & Tobacco Research, 2021
Kylie Morphett, Coral Gartner
openaire   +2 more sources

Forecasting heart failure: Seasonal alignment of heart failure outcomes in New York

ESC Heart Failure, Volume 12, Issue 2, Page 819-831, April 2025.
Abstract Background Seasonal variations have been observed in heart failure (HF) hospitalization. Numerous explanatory mechanisms have been proposed, but no prior studies have examined potential contributors directly. Our objective was to identify specific factors that could contribute to seasonal variability using a large longitudinal dataset of HF ...
Prerna Gupta, Ellen Brinza, Prateeti Khazanie, Pamela N. Peterson, P Michael Ho, David P. Kao   +5 more
wiley   +1 more source