Results 161 to 170 of about 84,016 (296)

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

Heart failure and tobacco use disorder: mortality trends and disparities in the United States. [PDF]

Ann Med Surg (Lond)
Mahmood A, Latif F, Latif S, Smith DN, Ayalew BD, Raja A, Kumar S, Kumar N, Rai KD, Sangtiani AK, Khan T, Hanif H, Kumar L, Bs A, Chaulagain A.   +14 more
europepmc   +1 more source

Electronic Cigarettes: an Overlooked Tool to Alleviate Disparities in Tobacco Use Disorder Among People with Mental Health and Substance Use Disorders. [PDF]

J Gen Intern Med, 2023
Vuong JT, Ruedisueli I, Beaudin CS, Middlekauff HR.   +3 more
europepmc   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

Effects of a Single Sub-Anesthetic Dose of Ketamine in Tobacco Use Disorder: An Active-Placebo, Randomized Crossover Study. [PDF]

Brain Sci
Luzum NR, McCall MH, Boyd CT, Columbano H, Ip E, Saldana S, Oliveto AH, Addicott M.   +7 more
europepmc   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto, Daniel Vitor de Souza, Gabriel Carvalhal de Aguiar, Ana Claudia Muniz Renno, Patricia Ramos Cury, Jean Nunes dos Santos, Rogerio Aparecido Dedivitis, Daniel Araki Ribeiro   +7 more
wiley   +1 more source

Tobacco use disorder is associated with increased risk of cardiomyopathy in a population-based study from Taiwan. [PDF]

Sci Rep
Yu PY, Hsin HT, Yu PC, Chung CH, Weng TH, Tsai CT, Wang BL, Huang SH, Chung RJ, Huang YC, Fann LY, Chien WC.   +11 more
europepmc   +1 more source

An Evaluation of Evidence Underpinning Management Recommendations in Tobacco Use Disorder Clinical Practice Guidelines. [PDF]

Nicotine Tob Res, 2022
Streck S, McIntire R, Canale L, Michael Anderson J, Hartwell M, Torgerson T, Dunn K, Vassar M.   +7 more
europepmc   +1 more source

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang, Binbin Ge, Ming Li, Xiaochun Xia, Fuming Zhang, Pengqin Xu   +5 more
wiley   +1 more source

Text Message (SMS) Microlearning for Tobacco Use Disorder: Pre-Post Pilot Study of Clinician Confidence. [PDF]

JMIR Med Educ
Dhanani Z, Dronamraju V, Garfield J.
europepmc   +1 more source