Tocolytic agents and the failure to improve neonatal outcomes
Abstract Premature delivery has long been a major problem in obstetrics. Increased perinatal morbidity and mortality as well as substantial health care costs, both short and long term, have driven the efforts to combat this complication. While multiple agents have been studied over the last 70 years leading to hundreds of publications and involving ...
Jack FitzSimmons, Emily Oliver
wiley +2 more sources
Tocolysis among Women with Preterm Birth: Associated Factors and Outcomes from a Multicenter Study in Brazil [PDF]
Objective To evaluate the use of tocolysis in cases of preterm birth due to spontaneous preterm labor in a Brazilian sample. Methods A sample of 1,491 women with preterm birth due to spontaneous preterm labor were assessed, considering treatment with ...
Tábata Z. Dias +9 more
openalex +4 more sources
School Performance After Maintenance Tocolysis With Nifedipine for Threatened Preterm Birth: 12-Year Follow-Up of the APOSTEL 2 Trial. [PDF]
ABSTRACT Objective To evaluate school performance at 12 years of age in children prenatally exposed to maintenance tocolysis with nifedipine versus placebo. Design 12‐year follow‐up of the multicentre APOSTEL 2 trial, in which participants with threatened preterm birth between 26+0 and 32+2 weeks of gestation, who remained pregnant after initial 48‐h ...
van der Windt LI +8 more
europepmc +2 more sources
The Experience and Outcomes of Rescue Cervical Cerclage at a Victorian Tertiary Hospital-A Retrospective Observational Study. [PDF]
ABSTRACT A rescue cervical cerclage is an emergency procedure aimed to prolong pregnancy and reduce the risk of preterm birth for women with an open cervix. This retrospective study assessed risk factors, perioperative management and outcomes for all attempted rescue cerclage over 3 years in a large tertiary hospital in Australia.
Phung M, Dawes L.
europepmc +2 more sources
Individual and organisational determinants associated with maintenance tocolysis in the management of preterm labour: a multilevel analysis. [PDF]
BackgroundClinical guidelines do not recommend maintenance tocolysis for the management of preterm labour. The French national survey EVAPRIMA revealed it was administered to more than 50% of women hospitalised for preterm labour. Our aim was to identify
Caroline Diguisto +7 more
doaj +1 more source
Risk of preterm delivery in women with a history of preterm labor successfully arrested by tocolytic treatment in their previous pregnancy. [PDF]
Introduction We aimed to determine if women with a history of preterm labor successfully arrested by tocolytic treatment who gave birth at term in their previous pregnancy are at an increased risk of preterm delivery in their next pregnancy. Material and
Quibel T +4 more
europepmc +2 more sources
Modern tocolysis and adverse effects of tocolytics [PDF]
Relevance. Toсolytic therapy is the only method that is used in the treatment of pregnant women with preterm labor. However, the effectiveness and safety of this therapy is still a matter of debate.
O R Baev +2 more
doaj +1 more source
Facility-Level Factors Associating Antenatal Corticosteroid Administration Rates and Subsequent Term Birth Rates: A Nationwide Cross-Sectional Observational Study Using the 2020-2022 Perinatal Registry Database in Japan. [PDF]
ABSTRACT Aim The antenatal corticosteroid (ACS) administration rate in Japan is low. To achieve both high coverage and low overtreatment of ACS, understanding of facility‐level factors is important. This study aimed to identify facility‐level factors associated with ACS coverage and overtreatment and simulate the potential consequences of increased ACS
Fuma K +8 more
europepmc +2 more sources
Ritodrine-associated Noncardiogenic Pulmonary Edema Diagnosed by Point-of-care Ultrasound: A Case Report of Twin Gestation. [PDF]
Ritodrine hydrochloride, a beta-adrenergic tocolytic agent, can rarely cause acute noncardiogenic pulmonary edema, particularly in patients with multiple gestations or comorbidities.
Chou CY, Chen CC.
europepmc +2 more sources
Tocolysis effects of traditional Chinese medicine and their effective components
Traditional Chinese medicine (TCM) for anti-abortion is based on the theory of gynecology of TCM, which aims to prevent and treat abdominal pain during pregnancy, fetal leakage, uneasy fetal movement, and fetal atrophy.
Tong-Hua Zhang +8 more
doaj +1 more source

