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Effect of tocolytic agents on fetal umbilical velocimetry
American Journal of Obstetrics and Gynecology, 1990In this prospective study, we sought to examine the changes in umbilical vascular resistance induced by tocolytic therapy. Umbilical artery velocimetry was performed in 46 patients with preterm labor before tocolysis and at 1 hour and 24 hours after tocolysis was initiated.
J W, Wright +3 more
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Magnesium sulfate as a tocolytic agent
American Journal of Obstetrics and Gynecology, 1983Magnesium sulfate (MgSO4) has been successfully used to inhibit premature labor. A retrospective review was performed on the use of MgSO4 as a tocolytic agent at Memorial Hospital, Long Beach, California, during a 4-year period (1978-1982). Three hundred fifty-five patients with diagnoses of premature labor were treated with MgSO4 after transport from ...
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Long-Term Use of Magnesium Sulfate as a Tocolytic Agent
Obstetrics & Gynecology, 1986Two patients in premature labor were treated continuously for six and 13 weeks with intravenous magnesium sulfate (MgSO4) for tocolysis. In each case, conventional therapy with intravenous and oral ritodrine failed to abate uterine contractions, and attempts to taper the MgSO4 were unsuccessful.
I A, Wilkins +5 more
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Complications Associated with the Administration of Tocolytic Agents
Journal SOGC, 1998Abstract Because maternal antenatal steroid administration has been shown to improve neonatal outcome at gestational age Jess then 34 weeks, many obstetrical practitioners choose to use tocolytic agents in an attempt to delay premature delivery and, thereby, allow enough time for steroid treatment. Unfortunately, tocolytics are not without potentially
Andrée Gruslin, Brigitte Bonin
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Progesterone as a tocolytic agent for preterm labor: a systematic review
Current Opinion in Obstetrics & Gynecology, 2016Purpose of review Tocolytic agents have been used for over 60 years in the fight against preterm labor, which ultimately can lead to preterm birth. Currently, clinicians can choose from a variety of drug classes to achieve the primary goal of delaying delivery by 48 h, thereby allowing time for administration of corticosteroids
Reshama, Navathe, Vincenzo, Berghella
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Prevention and Tocolytic Agents 2
2019Preterm birth is the single most important determinant of adverse infant outcomes, in terms of survival and quality of life. Preterm infants are particularly vulnerable to complications with the increasing contribution of neonatal deaths to overall child mortality.
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A Comparison of the Relative Toxicities of β-Sympathomimetic Tocolytic Agents
American Journal of Perinatology, 1985To define the relative toxicities of ritodrine sulfate, terbutaline sulfate, hexaprenaline sulfate, and ritodrine with betamethasone mongrel dogs were treated with these agents for 19 hours. The maximum dose of ritodrine was 900 microgram/min (N = 5), terbutaline 120 micrograms/min (N = 4) and hexaprenaline 1.5 micrograms/min (N = 4). Betamethasone was
G D, Hankins, J C, Hauth
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KUR-1246, a novel β2-adrenoceptor agonist, as a tocolytic agent
Obstetrics & Gynecology, 2002To examine the effects of KUR-1246 on oxytocin-induced uterine contractions, the cardiovascular system, and general metabolism of pregnant sheep and their fetuses.At 123-125 days' gestation, ewes (n = 8) were infused with oxytocin (1.0 mU/kg/minute) to induce uterine contractions.
Sumiyoshi, Kiguchi +5 more
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Uterine contraction agents, tocolytics, vaginal therapeutics, and local contraceptives
2007This chapter presents an account of drugs that play a role in strengthening or inhibiting uterine contraction, including tocolytics, vaginal therapeutics, and local contraceptives. These drugs include prostaglandins, oxytocin, ergot alkaloids, and β2-sympathicomimetics.
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Therapeutic Agents in Preterm Labor: Tocolytic Agents
Clinical Obstetrics and Gynecology, 2000A E, Hearne, D A, Nagey
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