Results 181 to 190 of about 3,661,902 (238)
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Magnesium sulfate as a tocolytic agent

American Journal of Obstetrics and Gynecology, 1983
Magnesium sulfate (MgSO4) has been successfully used to inhibit premature labor. A retrospective review was performed on the use of MgSO4 as a tocolytic agent at Memorial Hospital, Long Beach, California, during a 4-year period (1978-1982). Three hundred fifty-five patients with diagnoses of premature labor were treated with MgSO4 after transport from ...
openaire   +2 more sources

Fetal and neonatal effects of indomethacin used as a tocolytic agent

American Journal of Obstetrics and Gynecology, 1985
beta-Mimetic agents are currently recommended for tocolysis. Serious adverse reactions including maternal death may complicate their use. Prostaglandin synthetase inhibitors are effective tocolytic agents. Reports of potential adverse effects have limited clinical use in North America.
H, Zuckerman, E, Shalev
  +7 more sources

Design of oxytocin antagonists with prolonged action: potential tocolytic agents for the treatment of preterm labor.

Journal of Pharmacology and Experimental Therapeutics, 1986
In our continuing effort to produce more potent and specific oxytocin (OT) antagonists that may have value as tocolytic agents, we have synthesized a number of new OT antagonists.
W. Y. Chan   +3 more
semanticscholar   +1 more source

Tocolytic agents act on calcium channel current in single smooth muscle cells of pregnant rat uterus.

Journal of Pharmacology and Experimental Therapeutics, 1990
Effects of Ca2+ channel blockers and clinically important tocolytic agents, Mg2+ and beta-agonists, were examined on the Ca2+ channel current recorded from freshly isolated single pregnant rat myometrial cells using the whole-cell voltage clamp method ...
Y. Ohya, N. Sperelakis
semanticscholar   +1 more source

Long-Term Use of Magnesium Sulfate as a Tocolytic Agent

Obstetrics & Gynecology, 1986
Two patients in premature labor were treated continuously for six and 13 weeks with intravenous magnesium sulfate (MgSO4) for tocolysis. In each case, conventional therapy with intravenous and oral ritodrine failed to abate uterine contractions, and attempts to taper the MgSO4 were unsuccessful.
I A, Wilkins   +5 more
openaire   +2 more sources

Relationship between maternal mortality and ritodrine hydrochloride as a tocolytic agent in Japan

The journal of obstetrics and gynaecology research
In Japan, unlike Western countries, tocolytic agents are administered in long‐term protocols to treat threatened preterm labor. Evaluating the side effects of this practice is crucial.
Masamitsu Nakamura   +9 more
semanticscholar   +1 more source

Employing nifedipine as a tocolytic agent prior to external cephalic version

Acta Obstetricia et Gynecologica Scandinavica, 2008
AbstractBackground. External cephalic version (ECV) is accepted as a means of reducing the rate of breech presentation at term. Routine use of tocolysis prior to an ECV has been described to increase its success rate. The study's objective was to evaluate the efficacy of oral nifedipine as a tocolytic agent prior to ECV, and to compare it with ...
Raed, Salim   +4 more
openaire   +2 more sources

Progesterone as a tocolytic agent for preterm labor: a systematic review

Current Opinion in Obstetrics & Gynecology, 2016
Purpose of review Tocolytic agents have been used for over 60 years in the fight against preterm labor, which ultimately can lead to preterm birth. Currently, clinicians can choose from a variety of drug classes to achieve the primary goal of delaying delivery by 48 h, thereby allowing time for administration of corticosteroids
Reshama, Navathe, Vincenzo, Berghella
openaire   +2 more sources

A Comparison of the Relative Toxicities of β-Sympathomimetic Tocolytic Agents

American Journal of Perinatology, 1985
To define the relative toxicities of ritodrine sulfate, terbutaline sulfate, hexaprenaline sulfate, and ritodrine with betamethasone mongrel dogs were treated with these agents for 19 hours. The maximum dose of ritodrine was 900 microgram/min (N = 5), terbutaline 120 micrograms/min (N = 4) and hexaprenaline 1.5 micrograms/min (N = 4). Betamethasone was
G D, Hankins, J C, Hauth
openaire   +2 more sources

KUR-1246, a novel β2-adrenoceptor agonist, as a tocolytic agent

Obstetrics & Gynecology, 2002
To examine the effects of KUR-1246 on oxytocin-induced uterine contractions, the cardiovascular system, and general metabolism of pregnant sheep and their fetuses.At 123-125 days' gestation, ewes (n = 8) were infused with oxytocin (1.0 mU/kg/minute) to induce uterine contractions.
Sumiyoshi, Kiguchi   +5 more
openaire   +2 more sources

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