Results 71 to 80 of about 471,160 (266)

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

The Effects of Serial Casting on Children with Toe Walking: A Scoping Review

, 2022
The literature supports the use of serial casting as an effective intervention for toe walking. This intervention resulted in increased benefits when used in conjunction with co-interventions and should be considered by clinicians when treating children ...
Garcia, Grace, Gibbs, Brittany
core   +1 more source

Design of 3D printable prosthetic foot to implement nonlinear stiffness behavior of human toe joint based on finite element analysis

Scientific Reports, 2021
Toe joint is known as one of the critical factors in designing a prosthetic foot due to its nonlinear stiffness characteristic. This stiffness characteristic provides a general feeling of springiness in the toe-off and it also affects the ankle kinetics.
Hui-Jin Um, Heon-Su Kim, Woolim Hong, Hak-Sung Kim, Pilwon Hur   +4 more
doaj   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

Idiopathic toe walking: What’s New? An Integrative Review

Journal of the Foot & Ankle
Objective: Consolidate the current knowledge on idiopathic toe walking, provide a critical overview, and identify areas for potential future research. Methods: An electronic search was conducted in the following databases up to June 2023: MEDLINE, EBSCO,
Letícia D’Ordaz Lhano Santos, Talissa Oliveira Generoso, Luiz Renato Agrizzi de Angeli, Francesco Caamara Blumetti, Filipe Machado Barcelos   +4 more
doaj   +1 more source

Adjusting kinematics and kinetics in a feedback-controlled toe walking model

Journal of NeuroEngineering and Rehabilitation, 2012
Background In clinical gait assessment, the correct interpretation of gait kinematics and kinetics has a decisive impact on the success of the therapeutic programme.
Olenšek Andrej, Matjačić Zlatko
doaj   +1 more source

The dynamic characteristics of the center of pressure for toe-out gait: implications for footwear design

Journal of Leather Science and Engineering, 2022
Background Toe-out gait is often used as a conservative technique to reduce knee adduction moment, which has been targeted to modify knee osteoarthritis progression.
Bo Li, Xianyi Zhang
doaj   +1 more source

A Programmable Braided Silk‐Glass Fiber Ligament Promoting Rapid Motoric Recovery

Advanced Science, EarlyView.
A scalable three‐dimensional braiding strategy integrates silk and glass fibers into customizable artificial ligaments with programmable “J‐shaped” nonlinear mechanics. The silk‐rich architecture supports osseoligamentous integration, while glass fibers provide mechanical reinforcement and biomimetic mineralization cues, enabling strain‐adaptive load ...
Changbo Lu, Daming Liu, Haoxin Zhang, Zhiwei Qiao, Qiuming Gao, Jia Meng, Hongyin Yue, Songkai Li, Shuo Zhang, Tao Yuan, Yun Xue, Hui Jiang, Zhenguo Liu, Yibo Wang, Nirong Bao, Yuli Chen, Xiaojiang Yang   +16 more
wiley   +1 more source

Vibration Perception Thresholds in Children With Idiopathic Toe Walking Gait [PDF]

, 2020
This study investigated the vibration perception differences between children with an idiopathic toe walking gait and their non-toe walking peers. Sixty children, between the ages of four and eight years, were grouped into an idiopathic toe walking group

core  

Sports Activity Recognition Using Textile‐Based Sensor Fusion and Complex‐Valued Residual Convolutional Neural Networks

Advanced Intelligent Systems, EarlyView.
Motion artifacts in electrocardiographic signals, conventionally dismissed as noise, are shown to encode discriminative activity information. A smart t‐shirt fusing textile strain sensors with textile ECG electrodes, processed through a complex‐valued residual network, recognizes 12 sport activities.
Nada Al‐azzawi, Munire Sibel Cetin, Asli Tuncay Atalay, Ozgur Atalay, Gökhan Ince   +4 more
wiley   +1 more source