Results 251 to 260 of about 509,777 (301)

Off-Line Coupling of High-Resolution Capillary Electrophoresis to MALDI-TOF and TOF/TOF MS

Journal of Proteome Research, 2002
High-resolution capillary electrophoresis has been coupled to MALDI-TOF and TOF/TOF MS through off-line vacuum deposition onto standard stainless steel MALDI targets. This off-line approach allowed the decoupling of the separation from the MS analysis, thus allowing each to be independently optimized in terms of time.
Tomas, Rejtar, Ping, Hu, Peter, Juhasz, Jennifer M, Campbell, Marvin L, Vestal, Jan, Preisler, Barry L, Karger   +6 more
openaire   +2 more sources

TOF scatter estimation through TOF true distribution generation from non-TOF image reconstruction

IEEE Nuclear Science Symposuim & Medical Imaging Conference, 2010
An alternate methodology to estimate TOF scatter distribution is proposed. The scatter estimation is obtained by subtracting attenuated TOF true coincidence event estimations from measured TOF prompt coincidence events, corrected for random events and normalization.
openaire   +1 more source

Proteomic Analysisof Food Allergens by MALDI TOF/TOF Mass Spectrometry

2020
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is largely recognized as an important tool in the analysis of many biomolecules such as proteins and peptides. The MS analysis of digested peptides to identify a protein or some of its modifications is a key step in proteomics.
Cosima D. Calvano, Mariachiara Bianco, Ilario Losito, Tommaso Cataldi   +3 more
openaire   +3 more sources

Energy loss of 40Ar in Au: Comparison of TOF-E and TOF–TOF method

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2005
Abstract Energy loss of 40Ar ions in Au has been measured using two methods: TOF-E and TOF–TOF. The two methods are compared and discussed. The final results cover energy range 2–445 MeV (0.05–11 MeV/u) and give satisfactory agreement with SRIM 2003 predictions. Statistical error of the data is at the level of 1–2%.
J. Perkowski, W.H. Trzaska, J. Andrzejewski, V. Lyapin, T. Małkiewicz   +4 more
openaire   +1 more source

An Inexpensive, simple calibration method for MALDI TOF/TOF systems

Journal of Mass Spectrometry, 2019
AbstractThe array of analytes that can be measured by MADLI MS has created an equally vast range of calibration mixtures. The inherent problem with this is that acquiring all of them at commercial rates can be prohibitively expensive. With this in mind, we have created a low‐cost alternative to the most commonly used peptide calibrants.We were able to ...
Matthew B. O'Rourke, Matthew P. Padula
openaire   +2 more sources

Reflectron MALDI TOF and MALDI TOF/TOF mass spectrometry reveal novel structural details of native lipooligosaccharides

Journal of Mass Spectrometry, 2011
Lipooligosaccharides (LOS) are powerful Gram‐negative glycolipids that evade the immune system and invade host animal and vegetal cells. The structural elucidation of LOS is pivotal to understanding the mechanisms of infection at the molecular level.
L. Sturiale, A. Palmigiano, SILIPO, ALBA, Y. A. Knirel, A. P. Anisimov, LANZETTA, ROSA, PARRILLI, MICHELANGELO, MOLINARO, ANTONIO, D. Garozzo   +8 more
openaire   +4 more sources

MALDI-TOF Mass Spectrometry

2013
Major strengths of mass spectrometry analysis include the accuracy of the detection principle, automatic data storage as well as simplicity and flexibility of assay design making it a premier choice for targeted genotyping of sequence variations. We explain the assay principle in detail and give step-by-step laboratory instructions. Finally, references
Dirk, van den Boom, Matthias, Wjst, Robin E, Everts   +2 more
openaire   +2 more sources

ToF‐SIMS of polyphosphate glasses

Surface and Interface Analysis, 2012
The increasing interest in phosphate glasses is due to the fact that they are considered to be bioactive functional materials in applications such as hard and soft tissue engineering and also that they possess interesting optical properties.
Crobu M, ROSSI, ANTONELLA, Spencer ND
openaire   +3 more sources

MALDI-TOF/TOF CID Study of Polystyrene Fragmentation Reactions

Macromolecules, 2007
MALDI-TOF/TOF CID experiments were conducted on a variety of hydroxylated polystyrene precursor ions (m/z 1249.6 (n = 10), 1769.9 (n = 15), 2290.2 (n = 20), 2810.5 (n = 25), and 3330.8 (n = 30)) to examine the influence of molecular weight and collision kinetic energy on the degradation mechanisms. Our study indicates that polystyrene free radicals are
Anthony P. Gies, Matthew J. Vergne, Rebecca L. Orndorff, David M. Hercules   +3 more
openaire   +1 more source

MALDI–TOF/TOF CID Study of Polycarbodiimide Branching Reactions

Macromolecules, 2013
A combination of MALDI–TOF MS and TOF/TOF collision-induced dissociation (CID) experiments was conducted on toluene diisocyanate (TDI) based carbodiimide and phenyl isocyanate (PI) carbodiimide mixtures to examine their degradation mechanisms and identify “fingerprint” side products associated with each of their synthesis.
Anthony P. Gies, William H. Heath, Richard J. Keaton, Jorge J. Jimenez, Joseph J. Zupancic   +4 more
openaire   +1 more source