Use of SGLT2 (Sodium-Glucose Cotransporter 2) Inhibitors in Pulmonary Hypertension. [PDF]
Aguado B +11 more
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Pharmacological research of a novel selective SGLT2 inhibitor, tofogliflozin
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Metabolic Concepts of Sodium-Glucose Cotransporter 2 Inhibitors-Based Therapies Against Hepatocarcinogenesis and Therapy Resistance in Hepatocellular Carcinoma. [PDF]
Chung HH.
europepmc +1 more source
The Impact of Sodium Glucose Co-Transporter 2 (SGLT-2) Inhibitors on Atherogenesis: A Systematic Review of Experimental and Clinical Evidence. [PDF]
Gurgoglione FL +14 more
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The comparative efficacy of SGLT-2 inhibitors and GLP-1 receptor agonists on metabolic benefits in T2DM patients: a systematic review and network meta-analysis. [PDF]
Tong J, Li N, Hu F, Yue Y.
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Pharmacological profile of tofogliflozin, a novel SGLT2 inhibitor, in preclinical studies
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Pharmacological profile of tofogliflozin, a novel SGLT2 inhibitor, in preclinical studies
openaire
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European Journal of Clinical Pharmacology, 2023Studies have demonstrated a high prevalence of non-alcoholic fatty liver disease (NAFLD) in type 2 diabetes mellitus (T2DM) patients. The aim was to review the effect of tofogliflozin on hepatic outcomes in T2DM patients.A literature search in PubMed, Science Direct and Cochrane Central Register of Controlled Trials was conducted for randomised ...
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We investigated the salt cocrystals formed by tofogliflozin with sodium acetate and potassium acetate by determining the crystal structures of the salt cocrystals and characterizing the solid states. The salt cocrystal screening using the slurry method and the liquid-assisted grinding method resulted in the formation of tofogliflozin-sodium acetate 1 :
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