Results 41 to 50 of about 120,958 (302)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The use of modern digital technologies in public administration
The article examines and analyzes the possible path of development and use of cryptocurrencies in the Russian Federation in a comparative analysis with Europe and the United States as one rapidly developing sector of the economy.
T. A. Shebzukhova +2 more
doaj +1 more source
A Fault-Tolerant Token based Atomic Broadcast Algorithm [PDF]
Many atomic broadcast algorithms have been published in the last twenty years. Token based algorithms represent a large class of these algorithms. Interestingly, all the token based atomic broadcast algorithms rely on a group membership service and none ...
Schiper, André +3 more
core +3 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Using Telehealth as a Model for Blockchain HIT Adoption
Telemedicine and blockchain technology share a core philosophy of empowering the individual. Blockchain solutions that focus on empowering patients and enhancing the workflows for the providers who treat them continue to make big headlines, as does ...
Brennan Bennett
doaj +1 more source
A Reciprocal Relationship Between Bottom-up Trace Strength and the Attentional Blink Bottleneck: Relating the LC-NE and ST2 Models [PDF]
There is considerable current interest in neural modelling of the attentional blink phenomenon. Two prominent models of this task are the Simultaneous Type Serial Token (ST2) model and the Locus Coeruleus Norepinephrine (LC-NE) model. The former of these
Craston, Patrick +3 more
core +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Causal Models, Token-Causation and Processes [PDF]
This paper examines some counterexamples to Judea Pearl's theory of token-causation within his structural equations framework.
Menzies, Peter
core
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source

