Results 51 to 60 of about 152,555 (310)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Bridging Continuous and Discrete Tokens for Autoregressive Visual Generation [PDF]

IEEE International Conference on Computer Vision
Autoregressive visual generation models typically rely on tokenizers to compress images into tokens that can be predicted sequentially. A fundamental dilemma exists in token representation: discrete tokens enable straightforward modeling with standard ...
Yuqing Wang, Zhijie Lin, Yao Teng, Yuanzhi Zhu, Shuhuai Ren, Jiashi Feng, Xihui Liu   +6 more
semanticscholar   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Token Swapping on Trees

Discrete Mathematics & Theoretical Computer Science, 2023
The input to the token swapping problem is a graph with vertices $v_1, v_2, \ldots, v_n$, and $n$ tokens with labels $1, 2, \ldots, n$, one on each vertex. The goal is to get token $i$ to vertex $v_i$ for all $i= 1, \ldots, n$ using a minimum number of swaps, where a swap exchanges the tokens on the endpoints of an edge.
Ahmad Biniaz, Kshitij Jain 0001, Anna Lubiw, Zuzana Masárová, Tillmann Miltzow, Debajyoti Mondal, Anurag Murty Naredla, Josef Tkadlec, Alexi Turcotte   +8 more
openaire   +5 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Non-fungible tokens

Internet Policy Review, 2022
Blockchain-based NFTs (non-fungible tokens) are uniquely identifiable digital representations of physical or digital items. Usually, the tokens are indivisible into smaller units.
Florian Idelberger, Péter Mezei
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

A Case Study of 3rd Party Hardware: The Weakest Link in Google’s Trustworthy Artificial Intelligence Implementation

IEEE Access
The proliferated smart TV market has sparked a race among the tech giants to capture market share, with Google aggressively pursuing this domain through partnerships with third-party smart TV manufacturers.
Scott Lorenz, Stanley Stinehour, Anitha Chennamaneni, Abdul B. Subhani, Mohammad Nadim   +4 more
doaj   +1 more source

Blockchain in education

Informaciâ i Innovacii, 2020
The article reveals the role and importance of blockchain technology in education, provides a mechanism for solving educational problems with blockchain, describes specific educational projects based on blockchain technology: registry of diplomas ...
V. Grigoriev
doaj   +1 more source

NON-FUNGIBLE TOKENS

International Journal of Law in Changing World, 2023
The paper examines the concept of ownership and its potential application to digital assets, particularly Non-Fungible Tokens (“NFTs”). Technological advancements which allow the creation, storage, and sale of unique digital assets in a purely digital ...
Matteo Alessandro
doaj   +1 more source