Results 31 to 40 of about 1,738,131 (340)

Transforming a Central Tokyo Park Into a Cutting‐Edge Commercial Complex: Miyashita Park, Shibuya

open access: yesUrban Planning
This study examines a case of urban renewal in Shibuya, one of Tokyo’s most prominent downtown areas, featuring Miyashita Park, a dilapidated 10,000‐square‐meter park that transformed into a modern commercial complex consisting of a multistory commercial
Junichi Hasegawa
doaj   +1 more source

Explosive Nucleosynthesis in GRB Jets Accompanied by Hypernovae [PDF]

open access: yes, 2006
Two-dimensional hydrodynamic simulations are performed to investigate explosive nucleosynthesis in a collapsar using the model of MacFadyen and Woosley (1999).
/Garching, Max Planck Inst.   +5 more
core   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Night‐Time Urbanism and Sustainable Regeneration: Play, Public Space, and Revitalisation in Tokyo and Melbourne

open access: yesUrban Planning
As cities navigate the challenges of commercial decline, suburbanisation, and demographic transition, night‐time urbanism has emerged as a critical yet underexplored dimension of sustainable urban regeneration. This article positions “night play” as both
Sidh Sintusingha, Alice Covatta
doaj   +1 more source

Transnational professionals’ socio-spatial venturing out to the Tokyo global city-region

open access: yesRegional Studies, Regional Science, 2019
Global-city research has focused primarily on considering transnational corporations and transnational professionals (TNPs) in economic terms, neglecting the role of TNPs’ specific socio-spatial practices in constituting the transnational space. Although
Sakura Yamamura
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The role of ad hoc tribunals in the implementation of cosmopolitan law: an empirical study via Kantian ethics

open access: yesAnnales de la Faculté de Droit d’Istanbul
The suffering inflicted on vulnerable people has attracted the interest of many thinkers since Antiquity. From Stoics to contemporary peace theorists, many scholars have proposed ways to prevent such suffering and achieve perpetual peace. This phenomenon
Başak Naz Şimşek   +1 more
doaj   +1 more source

Changes in Marine Seafood Consumption in Tokyo, Japan

open access: yesDesenvolvimento e Meio Ambiente, 2012
This article examines the historical trends of Tokyo’s marine seafood consumption and tensions over how to promote urban sustainable consumption. Despite overwhelming evidence that global fish stocks are depleting, the Tokyo Metropolitan Government has ...
Tatiana Maria Cecy Gadda   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy