Results 41 to 50 of about 1,738,131 (340)

Cities & International Policy Diffusion: The Case of Tokyo

Baltic Journal of European studies, 2019
In an increasingly globalised world, today’s international challenges such as climate change transcend national boundaries and require multi-level governance responses.
Chiu Nikita
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Nuclear Excitations Described by Randomly Selected Multiple Slater Determinants [PDF]

, 2006
We propose a new stochastic method to describe low-lying excited states of finite nuclei superposing multiple Slater determinants without assuming generator coordinates a priori.
H Ohta, K Yabana, Ring P, S Shinohara, T Nakatsukasa   +4 more
core   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Chiyoda Life Insurance Company Headquarters in Tokyo

Docomomo Journal, 2022
In Tokyo, a masterpiece of modern architecture, built after the war, has found a new role as a public building. The district's office of Meguro-ku {Tokyo) has iust moved to a facility designed by the famous architect Togo Murano ( 1 891 -1984 ).
Hiroyasu Fujioka
doaj   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Investigating a unilateral pleural effusion: A tale of a medical error and diagnostic delays

Lung India, 2017
We report the case of an elderly Asian man where a medical error and diagnostic delays obscured the diagnosis of pleural tuberculosis (TB). The patient was hospitalized for evaluation of a unilateral pleural effusion. Initially, the patient was subjected
Suminda Welagedara, Tokyo Moe Swe, Krishna Bajee Sriram   +2 more
doaj   +1 more source

Recent advances in the theory of nuclear forces [PDF]

, 2006
After a brief historical review, we present recent progress in our understanding of nuclear forces in terms of chiral effective field theory.Comment: 6 pages, 2 figures; talk at International Symposium on Correlations Dynamics in Nuclei, University of ...
, , , , D R Entem, Forssen C, Machleidt R, Nagels M M, Navrátil P, R Machleidt, R Vinh Mau R, Taketani M, Weinberg S, Yukawa H   +13 more
core   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

From futuristic center to lifeless periphery: Tokyo in three dystopian narratives from post-Fukushima Japan

Dive-In
Reflections on the collective traumas that have shaped Japan’s more recent history (primarily the triple disaster of Fukushima) have ignited a new boom in dystopian productions that have achieved an unprecedented success.
Giulia Colelli
doaj   +1 more source