Results 121 to 130 of about 610 (158)
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Methylene blue or tolonium chloride antagonism of sodium nitrite induced methemoglobinemia
Journal of Veterinary Pharmacology and Therapeutics, 1979Methylene blue is widely accepted as an antidote for nitrite toxicosis because of its ability to stimulate reduction of methemoglobin (ferrihemoglobin) to hemoglobin. It is usually used only in low dosage (4mg/kg) because of its purported enhancement of methemoglobin formation in high dosages.
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Head & Neck, 2003
AbstractBackground.The clinical utility of tolonium chloride rinse was compared with unaided visual examination alone in the diagnosis of oral carcinoma in patients previously treated for carcinoma of the upper aerodigestive tract.Methods.A total of 668 patients were enrolled in this multicenter study.
Joel B, Epstein +3 more
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AbstractBackground.The clinical utility of tolonium chloride rinse was compared with unaided visual examination alone in the diagnosis of oral carcinoma in patients previously treated for carcinoma of the upper aerodigestive tract.Methods.A total of 668 patients were enrolled in this multicenter study.
Joel B, Epstein +3 more
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Pharmacokinetics and toxicity of tolonium chloride in sheep.
Veterinary and human toxicology, 1997The pharmacokinetic disposition, urinary excretion and toxicity of tolonium chloride were determined after i.v. administration to sheep. Pretreatment with sodium nitrite significantly decreased the volume of the central compartment, apparent volume of distribution, area under the concentration-time curve, and total body clearance of tolonium chloride ...
L A, Cudd, G E, Burrows, C R, Clarke
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Journal of Pharmaceutical Sciences, 1967
The intraperitoneal administration of propoxyphene HCI to albino mice at a dosage level of 200 mg./Kg. (LD 99.5 ) was lethal to 98 per cent of the controls. The prophylactic subcutaneous administration of nalorphine HC1 alone, or in combination with either methylene blue or tolonium chloride, significantly increased the number of survivors with the ...
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The intraperitoneal administration of propoxyphene HCI to albino mice at a dosage level of 200 mg./Kg. (LD 99.5 ) was lethal to 98 per cent of the controls. The prophylactic subcutaneous administration of nalorphine HC1 alone, or in combination with either methylene blue or tolonium chloride, significantly increased the number of survivors with the ...
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The Journal of the American Dental Association, 1983
Tolonium chloride rinse is proposed as a cancer screening agent to be used after thorough soft tissue examination. Historical review and clinical observations show no toxicity or untoward results from its topical use.
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Tolonium chloride rinse is proposed as a cancer screening agent to be used after thorough soft tissue examination. Historical review and clinical observations show no toxicity or untoward results from its topical use.
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Der Anaesthesist, 2011
A 22-year-old patient underwent surgery for a glass wound incision of the hand and anesthesia was carried out using an axillary brachial plexus block with prilocaine. Following surgery the patient developed methemoglobinemia which was treated with tolonium chloride. After administration of the drug the sinus rhythm changed into ventricular fibrillation.
O C, Radke +3 more
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A 22-year-old patient underwent surgery for a glass wound incision of the hand and anesthesia was carried out using an axillary brachial plexus block with prilocaine. Following surgery the patient developed methemoglobinemia which was treated with tolonium chloride. After administration of the drug the sinus rhythm changed into ventricular fibrillation.
O C, Radke +3 more
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Cancer research, 1988
Pyronin Y [3,6-bis(dimethylamino)xanthylium chloride; PY] and toluidine blue O [tolonium chloride; 3-amino-7-(dimethylamino)-2-methyl phenothiazin-5-ium chloride; TB] are cationic dyes commonly used in cytochemistry that have affinity to nucleic acids, predominantly to RNA.
Z, Darzynkiewicz, S P, Carter
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Pyronin Y [3,6-bis(dimethylamino)xanthylium chloride; PY] and toluidine blue O [tolonium chloride; 3-amino-7-(dimethylamino)-2-methyl phenothiazin-5-ium chloride; TB] are cationic dyes commonly used in cytochemistry that have affinity to nucleic acids, predominantly to RNA.
Z, Darzynkiewicz, S P, Carter
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly