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Tolosa-Hunt syndrome after chikungunya infection [PDF]
Revista Brasileira de OftalmologiaThis case report aimed to describe the Tolosa-Hunt syndrome in a patient infected with chikungunya and highlight the relevance of considering chikungunya as a possible cause of the Tolosa-Hunt syndrome, especially in endemic or epidemic infection sites ...Celso Busnelo Moreno, Jade Pinto de Queiroz Guerra, João Marcelo Cecílio Ribeiro, Guilherme Novoa Colombo-Barboza, Marcello Novoa Colombo-Barboza, Priscilla Fernandes Nogueira +5 moredoaj +1 more sourceDiscordance of Dopaminergic Dysfunction and Subcortical Atrophy by α‐Synuclein Status in Sporadic and Genetic Parkinson's Disease
Movement Disorders, Volume 41, Issue 5, Page 1101-1113, May 2026.Abstract Background
Parkinson's disease (PD) is characterized by predominantly neuronal α‐synuclein pathology and dopaminergic dysfunction. Cerebrospinal fluid (CSF) seeding amplification assays (SAA) detect α‐synuclein aggregates in vivo, but not all patients with PD have a positive SAA.Michael Tran Duong, Sandhitsu R. Das, Pulkit Khandelwal, Joaquin A. Vizcarra, Yue Li, Long Xie, Paul A. Yushkevich, Leslie M. Shaw, Jacob G. Dubroff, Parkinson's Progression Markers Initiative, Kenneth Marek, Shirley Lasch, Caroline Tanner, Tanya Simuni, Christopher Coffey, Karl Kieburtz, Renee Wilson, Brit Mollenhauer, Site Investigator, Douglas Galasko, Site Investigator, Tatiana Foroud, Lana Chahine, Andrew Siderowf, John Seibyl, Arthur Toga, Andrew Singleton, Daniel Weintraub, John Trojanowski, Leslie Shaw, Duygu Tosun‐Turgut, Kathleen Poston, Susan Bressman, Kalpana M. Merchant, Werner Poewe, Todd Sherer, Sohini Chowdhury, Mark Frasier, Catherine Kopil, Anna Naito, Vanessa Arnedo, Ray Dorsey, Cynthia Casaceli, Imaging Core, Nichole Daegele, Justin Albani1 Statistics Core, Chelsea Caspell‐Garcia, Liz Uribe, Eric Foster, Jeff Long, Nick Seedorff, Karen Crawford, Danielle Elise Smith, Paola Casalin, Giulia Malferrari, Cheryl Halter, David Russell, Stewart Factor, Penelope Hogarth, David Standaert, Amy Amara, Robert Hauser, Joseph Jankovic, Matthew Stern, Shu‐Ching Hu, Gretchen Todd, Rachel Saunders‐Pullman, Irene Richard, Marie H Saint‐Hilaire, Klaus Seppi, Holly Shill, Hubert Fernandez, Claudia Trenkwalder, Wolfgang Oertel, Daniela Berg, Kathrin Brockman, Isabel Wurster, Liana Rosenthal, Yen Tai, Nicola Pavese, Paolo Barone, Stuart Isaacson, Alberto Espay, Dominic Rowe, Melanie Brandabur, James Tetrud, Grace Liang, Alex Iranzo, Eduardo Tolosa, Karen Marder, Maria de Arriba Sanchez, Leonidis Stefanis, Maria Jose Marti, Javier Ruiz Martinez, Jean‐Christophe Corvol, Jan O Assly, Salima Brillman, Nir Giladi, Debra Smejdir, Julia Pelaggi, Farah Kausar, Linda Rees, Barbara Sommerfield, Madeline Cresswell, Courtney Blair, Karen Williams, Grace Zimmerman, Stephanie Guthrie, Ashlee Rawlins, Leigh Donharl, Christine Hunter, Baochan Tran, Abigail Darin, Carly Linder, Marne Baca, Heli Venkov, Cathi‐Ann Thomas, Raymond James, Beatrice Heim, Paul Deritis, Fabienne Sprenger, Deborah Raymond, Diana Willeke, Zoran Obradov, Jennifer Mule, Nancy Monahan, Katharina Gauss, Deborah Fontaine, Daniel Szpak, Arita McCoy, Becky Dunlop, Laura Marie Payne, Susan Ainscough, Lisbeth Carvajal, Rebecca Silverstein, Kristy Espay, Madelaine Ranola, Elisabet Mondragon Rezola, Helen Mejia Santana, Maria Stamelou, Alicia Garrido, Stephanie Carvalho, Anne Grete Kristiansen, Krista Specketer, Anat Mirlman, Maurizio Facheris, Holly Soares, Mark A. Mintun, Jesse Cedarbaum, Peggy Taylor, Danna Jennings, Lawrence Slieker, Brian McBride, Colin Watson, Etienne Montagut, Zulfiqar Haider Sheikh, Baris Bingol, Remi Forrat, Pablo Sardi, Tanya Fischer, Alastair D. Reith, Jan Egebjerg, Lone Frydelund Larsen, Nathalie Breysse, Didier Meulien, Barbara Saba, Vera Kiyasova, Chris Min, Thomas McAvoy, Robert Umek, Philip Iredale, Jeremy Edgerton, Susan De Santi, Christian Czech, Frank Boess, Jeffrey Sevigny, Thomas Kremer, Igor Grachev, Kaplana Merchant, Andreja Avbersek, Pierandrea Muglia, Alexandra Stewart, Rene Prashad, Johannes Taucher, Andrew Siderowf, David A. Wolk, Ilya M. Nasrallah +186 morewiley +1 more sourceReal‐World Evaluation of the BioFire FilmArray ME Panel: Diagnostic Accuracy and Clinical Utility
Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.Central nervous system (CNS) infections carry high morbidity and mortality, yet traditional diagnostics often fail to identify the causative agent promptly. Rapid multiplex panels offer broader and faster pathogen detection, making it important to understand their real‐world clinical value.Mehmet Erinmez, Mustafa Sağlam, Gönenç Çalışkantürk, Merve Özerol, Yasemin Zer, Marcos Christian Bautista +5 morewiley +1 more sourceA 17-Year-Old Girl With Unilateral Headache and Double Vision
Journal of Investigative Medicine High Impact Case Reports, 2019 Tolosa-Hunt syndrome is characterized by a painful ophthalmoplegia secondary to a granulomatous inflammation in or adjacent to the cavernous sinus. Magnetic resonance imaging will show enhancement of the cavernous sinus and/or the orbital apex.Larissa G. Rodriguez-Homs MBS, Mark Goerlitz-Jessen MD, Samrat U. Das MD +2 moredoaj +1 more sourceTolosa-Hunt Syndrome – Case Report
Acta Clinica Croatica, 2017 This case report presents a patient diagnosed with Tolosa-Hunt syndrome (THS) after an extensive neuro-diagnostic and neuroimaging evaluation. Diagnostic work-up included thorough physical and neurological examination, complete laboratory serum ...Sandra Zečević Penić, Marijana Lisak, Tomislav Gregurić, Hrvoje Hećimović, Vanja Bašić Kes +4 moredoaj +1 more sourceTolosa-Hunt syndrome after COVID-19 infection
Cephalalgia Reports, 2022 Tolosa-Hunt syndrome (THS) is a rare, idiopathic, non-specific inflammation within the cavernous sinus and/or superior orbital fissure leading to painful ophthalmoplegia.Tyler Etheridge, Jordan Jones, Eric L Caskey, Kathleen B Digre, Judith EA Warner, Meagan D Seay +5 moredoaj +1 more sourceDOTATATE Scan in Meningiomatosis in a Patient With Ophthalmoplegia
Case Reports in Ophthalmological Medicine, Volume 2026, Issue 1, 2026.DOTATATE (1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraacetic acid [DOTA]‐octreotate) is a compound that binds somatostatin receptors seen in tumors such as meningiomas. Here, we present a case of a patient with progressive bilateral ophthalmoplegia due to meningiomatosis involving both cavernous sinuses, which was highlighted by DOTATATE imaging. Some Joshua Pasol, Carolina G. Benjamin, W. David Honeycutt, Cristiano Giusti +3 morewiley +1 more sourceIs it time to retire the Tolosa-Hunt syndrome?
, 2021 A 63-year-old man presented with a 2-month history of progressive right-sided exophthalmos, painful ophthalmoplegia and fevers. As more features developed, he was diagnosed with giant cell arteritis, then Tolosa-Hunt syndrome, and transiently responded ...Lueck, Christiancore +1 more sourceOcular Misalignment and Motility Limitation in Orbital Tumors
Journal of Ophthalmology, Volume 2026, Issue 1, 2026.Purpose
To predict prognosis and aid in the treatment of residual strabismus/ocular misalignment by analyzing the pattern of ocular motility disturbances caused by orbital tumors, and investigating factors associated with the severity of misalignment or motility limitation.Min Seok Kang, Namju Kim, Hee Kyung Yang, Jeong-Min Hwang, Shweta Negi +4 morewiley +1 more source