Results 161 to 170 of about 2,315 (209)

Ternary Solid Dispersions as an Alternative Approach to Enhance Pharmacological Activity. [PDF]

Drug Des Devel Ther
Amaliah S, Aulifa DL, Gazzali AM, Budiman A.   +3 more
europepmc   +1 more source

Zinc Complexes of Fluorosubstituted N-[2-(Phenyliminomethyl)phenyl]-4-methylbenzenesulfamides: Synthesis, Structure, Luminescent Properties, and Biological Activity. [PDF]

Materials (Basel)
Burlov AS, Vlasenko VG, Milutka MS, Koshchienko YV, Lazarenko VA, Trigub AL, Kolodina AA, Zubenko AA, Braga EV, Gusev AN, Linert W.   +10 more
europepmc   +1 more source

First insights on the susceptibility of native coccidicidal fungi Mucor circinelloides and Mucor lusitanicus to different avian antiparasitic drugs. [PDF]

BMC Vet Res
Lozano J, Cunha E, de Carvalho LM, Paz-Silva A, Oliveira M.   +4 more
europepmc   +1 more source

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Plasma disposition of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, in rabbits after oral administration

Veterinary Parasitology, 2010
The objective of this study was to evaluate the pharmacokinetic profiles of toltrazuril (TZR), and its major metabolites toltrazuril sulfoxide (TZR x SO) and toltrazuril sulfone (TZR x SO(2)) in rabbits after oral administrations. Rabbits were dosed once with 10 and 20mg/kg TZR via stomach tube with manual restraint.
Youn-Hwan Hwang
exaly   +3 more sources

Deposition and depletion of the coccidiostats toltrazuril and halofuginone in eggs

Analytica Chimica Acta, 2005
Abstract Toltrazuril (TZ), a triazinetrione derivative, and halofuginone (HFG), a quinazolinone derivative, have been licensed for the prevention and treatment of coccidiosis in broilers and turkeys, but have been excluded for use in laying hens. Little is known regarding the deposition of residues of toltrazuril and halofuginone in eggs and their ...
Bjorn Berendsen
exaly   +3 more sources

Coccidiosis Control with Toltrazuril in Conjunction with Anticoccidial Medicated or Nonmedicated Feed

Avian Diseases, 2003
A 42-day broiler floor pen study was conducted comparing the anticoccidial efficacy of toltrazuril (Baycox) as a stand alone treatment and as an additional treatment to in-feed anticoccidial programs. Toltrazuril was administered on days 18 and 19 in the drinking water at 7 mg/kg of body weight.
G F, Mathis, R, Froyman, T, Irion, T, Kennedy   +3 more
exaly   +3 more sources

Pharmacokinetics of toltrazuril and its metabolite, toltrazuril sulfone, in suckling piglets following oral and intramuscular administrations

Journal of Veterinary Pharmacology and Therapeutics, 2023
AbstractToltrazuril (TZR) is currently the only registered chemotherapeutic drug in the European Union for the treatment of Cystoisospora suis. This study investigated the comparative pharmacokinetics and tissue concentration‐time profiles of TZR and its active metabolite, toltrazuril sulfone (TZR‐SO2), after oral (per os, p.o.) and intramuscular (i.m.)
Ta‐Wei Yeh, Tirawat Rairat, Chao‐Ming Wang, Ching‐Fen Wu, Szu‐Wei Huang, Chi‐Chung Chou, Hung‐Chih Kuo   +6 more
openaire   +2 more sources

Migration and toxicity of toltrazuril and its main metabolites in the environment

Chemosphere, 2022
Veterinary drugs heavily used in livestock are passed into the environment through different ways, resulting in risks to terrestrial environments and humans. The migration of toltrazuril (TOL), an important anticoccidial drug used intensively in livestock, and its main metabolites between the chicken manure compost, soil and vegetables was investigated,
Meixia Huo, Wenjin Ma, Kaixiang Zhou, Xiangyue Xu, Zhenli Liu, Lingli Huang   +5 more
openaire   +2 more sources

Solubility of Toltrazuril and the Effect of a Cosolvent

Journal of Chemical & Engineering Data, 2018
The purpose of this work is to study the dissolution process of toltrazuril and the influence of the solvent on solubility.
Yüfang Wu, Jiaqin Wu, Long Cheng, Jiachao Wang   +3 more
openaire   +1 more source

Efficacy of toltrazuril against intestinal and hepatic coccidiosis in rabbits

Veterinary Parasitology, 1986
The anticoccidial effect of toltrazuril (Bay Vi 9142) against Eimeria flavescens, E. intestinalis, E. magna, E. perforans and E. stiedai was tested in experimentally-infected rabbits. Continuous administration of 10-15 p.p.m. of the drug in the drinking water was highly effective in reducing oocyst output of all five species and in preventing clinical ...
J E, Peeters, R, Geeroms
openaire   +2 more sources