Results 21 to 30 of about 9,892 (240)
Holger Schirutschke, Peter Gross, Alexander Paliege, Christian Hugo University Hospital Carl Gustav Carus at the Technische, Universität Dresden, Department of Internal Medicine III, Division of Nephrology, Dresden, GermanyCorrespondence: Holger ...
Schirutschke H +3 more
doaj
Effectiveness of Tolvaptan Treatment in Hyponatremic Patients
Objective: Non-peptide vasopressin receptor antagonists (vaptans) are effective at increasing sodium in euvolemic and hypervolemic states and appear safe. We aimed to evaluate the efficacy of tolvaptan in euvolemic or hypervolemic hyponatremic patients.
Mehmet Fethullah Aydın +4 more
doaj +1 more source
Background: Tolvaptan is a vasopressin type 2 receptor antagonist used in heart failure (HF) with refractory diuretic resistance. However, since tolvaptan is also ineffective in some HF patients with reduced ejection fraction (HFrEF), the identification ...
Shinichi Nonin +9 more
doaj +1 more source
Heart failure (HF) is often complicated by renal dysfunction. Tolvaptan and valsartan are two well-known agents for the treatment of HF. However, the role of tolvaptan/valsartan combination on HF with renal dysfunction remains unclear.
Fengqin Yan +4 more
doaj +1 more source
Hyponatremia : Special Considerations in Older Patients [PDF]
Acknowledgments Roy L.
Clarke, Jennifer M +4 more
core +2 more sources
Tolvaptan for the treatment of the syndrome of inappropriate antidiuresis (SIAD)
The syndrome of inappropriate antidiuresis (SIAD), the commonest cause of hyponatraemia, is associated with significant morbidity and mortality. Tolvaptan, an oral vasopressin V2-receptor antagonist, leads through aquaresis to an increase in serum sodium
Ploutarchos Tzoulis +4 more
doaj +1 more source
Improving Postdischarge Outcomes in Acute Heart Failure [PDF]
The global burden that acute heart failure (AHF) carries has remained unchanged over the past several decades (1). European registries (2–5) showed that 1-year outcome rates remain unacceptably high (Table 1) and confirm that hospitalization for AHF ...
Ambrosy, Andrew P. +8 more
core +1 more source
Unveiling some FDA-approved drugs as inhibitors of the store-operated Ca2+ entry pathway. [PDF]
The store-operated calcium entry (SOCE) pathway is an important route for generating cytosolic Ca2+ signals that regulate a diverse array of biological processes.
Rahman, Saifur, Rahman, Taufiq
core +2 more sources
Tolvaptan Attenuates Left Ventricular Fibrosis After Acute Myocardial Infarction in Rats
Tolvaptan, a non-peptide V2-receptor antagonist, is a newly developed diuretic agent. Recently, we reported that tolvaptan has diuretic as well as anti-inflammatory and anti-fibrotic actions in chronic heart failure.
Takanori Yamazaki +10 more
doaj +1 more source
Renoprotective effect of tolvaptan in patients with new‐onset acute heart failure
Aims Although tolvaptan has been reported to prevent worsening renal function (WRF) in patients with advanced acute heart failure (AHF), evidence regarding the effect of tolvaptan on renal function in patients with new‐onset AHF is not available.
Hiromi Kin +10 more
doaj +1 more source

