Results 131 to 140 of about 7,163 (266)

Computation‐Guided Tunnel Engineering Enhances O2 Transport and H2O2 Resistance of Fe(II)/α‐Ketoglutarate‐Dependent Dioxygenases

open access: yesAdvanced Science, EarlyView.
This study presents a computational tunnel engineering strategy in Fe(II)/α‐ketoglutarate‐dependent dioxygenases (αKGDs) to enhance oxygen (O2) transport, an essential molecule for αKGDs, and limit hydrogen peroxide (H2O2) entry, an inhibitor from the αKG supply system.
Huan Liu   +10 more
wiley   +1 more source

Analysis of the Fiber Residues Unearthed from the Dabuzi Han Tomb in Xi'an, Shaanxi. [PDF]

open access: yesMaterials (Basel)
Ma Z   +7 more
europepmc   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

open access: yesAdvanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya   +10 more
wiley   +1 more source

Funerary practices of cremation at the megalithic societies of South-Eastern Iberia: The cemetery of Los Milanes. [PDF]

open access: yesPLoS One
Becerra Fuello P   +9 more
europepmc   +1 more source

Freestanding Bamboo‐Like Nitrogen‐Doped Carbon Nanofibers/PANI Dual‐Conductive Cathodes via Interfacial Engineering for High‐Performance Lithium–Sulfur Batteries

open access: yesAdvanced Science, EarlyView.
Bamboo‐like nitrogen‐doped carbon fibers (BNCFs) were synthesized via a vapor‐liquid‐solid catalytic growth method and further integrated with polyaniline to fabricate a freestanding BNCFs/S/PANI cathode. The PANI coating and BNCFs framework synergistically establish an interconnected conductive network with abundant nitrogen‐active sites, thereby ...
Jie Yang   +5 more
wiley   +1 more source

Multi‐Stimuli Responsive Magneto‐Coacervate Droplets for Selective Molecular Enrichment and Programmable Manipulation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Coacervate droplets formed via liquid–liquid phase separation offer unique opportunities as microreactors and delivery vehicles due to their ability to selectively concentrate biomolecules and support biochemical reactions. However, their passive nature severely restricts precise spatial and temporal control, posing barriers to practical ...
Kailang Liu   +6 more
wiley   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li   +15 more
wiley   +1 more source

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