Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
Measuring Equine Hooves in Radiographs and Computed Tomography Images Reveals Unexpected Size Differences. [PDF]
Sellke L +3 more
europepmc +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Portable Cone-Beam Computed Tomography System for Intraoperative Localization of Pulmonary Nodules: An Initial Experience. [PDF]
Mitsuoka M +7 more
europepmc +1 more source
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
The Use of Spatially Fractionated Radiation Therapy Combined With Immune Checkpoint Inhibitors and Vascular Endothelial Growth Factor Inhibitor in the Treatment of Giant Metastatic Hepatocellular Carcinoma: A Case Report. [PDF]
Jin Y +5 more
europepmc +1 more source
Anterior Segment Optical Coherence Tomography in the Diagnosis of Corneal Stromal Dystrophies in Romania. [PDF]
Gheorghe AG +4 more
europepmc +1 more source
Lessons from a misdiagnosed maternal pulmonary embolism: A case report and literature review. [PDF]
Chi P +6 more
europepmc +1 more source
Malignant skin adnexal tumor of the finger with late metastases. [PDF]
Erfani MH +3 more
europepmc +1 more source

