Results 201 to 210 of about 1,058,558 (285)

Rest‐activity patterns across development in two mouse models of autism and epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Sleep disturbances are common in individuals with autism spectrum disorder (ASD) and epilepsy and are increasingly recognized as comorbidities that affect disease severity and quality of life. This study investigated rest‐activity patterns across development in two genetic mouse models relevant to ASD and epilepsy: synapsin 2 (Syn2 ...
Ipsa Dash   +4 more
wiley   +1 more source

Disrupted cerebellar networks in uncontrolled focal to bilateral tonic–clonic seizures

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Focal to bilateral tonic–clonic seizures (FBTC) are associated with significant morbidity and an elevated risk of sudden unexpected death in epilepsy (SUDEP). The cerebellum has been implicated in modulating the frequency and severity of tonic–clonic seizures.
John Phamnguyen   +4 more
wiley   +1 more source

Phenotype‐guided etiologic workup in a prospective cohort of 144 adults with developmental and epileptic encephalopathy

open access: yesEpilepsia Open, EarlyView.
Abstract Objectives Adults with developmental and epileptic encephalopathies (DEEs) often enter adult neurology care without etiologic clarification because of incomplete transition from pediatric services, outdated investigations, and attenuation of childhood electro‐clinical features over time.
Giuseppe d’Orsi   +10 more
wiley   +1 more source

Auditory gamma‐band synchronization and attentional performance in juvenile myoclonic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Cognitive difficulties in juvenile myoclonic epilepsy (JME) are part of the clinical phenotype alongside epileptic seizures; however, the underlying neurophysiological mechanisms remain unclear. Auditory steady‐state responses (ASSRs) to repetitive 40‐ and 80‐Hz stimuli are widely used measures of gamma‐band oscillations (GBOs ...
Ryo Mitoma   +12 more
wiley   +1 more source

Neurometabolite abnormalities and associations with epilepsy duration and cognition in patients with idiopathic generalized epilepsies

open access: yesEpilepsia Open, EarlyView.
Abstract Objective This study investigated whether idiopathic generalized epilepsies (IGEs) are associated with neuroinflammation by measuring neurometabolite levels and brain temperature using whole‐brain magnetic resonance spectroscopy imaging (MRSI).
Yun Lien   +11 more
wiley   +1 more source

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