Results 131 to 140 of about 579,102 (295)
Ternary spreading and the OCP in Copperbelt Bemba
Studies in African Linguistics, 2013 Bemba tonology has been described with respect to two prominent claims: H tone local spreading is binary, and is blocked by the OCP. These claims are based on Bemba, as spoken in Northern Zambia.
Lee S. Bickmore, Nancy S. Kula
doaj
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Studies in African Linguistics, 1991 Bandi tonology offers three points of interest. The first is low tone opacity. Several tone rules act to obscure the presence of underlying low tones in Bandi.
Robert Mugele, Michael Rodewald
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tone-Word Recognition in Mandarin Chinese: Influences of lexical-level representations
, 2018 To recognise a spoken word, one has to access the phonological knowledge of this word mentally represented at a lexical (whole-word) level and the knowledge of consonants and vowels encoded at a sublexical level.
Jinxing Yue (12299150)
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
TONE MAPPING OPTIMIZATION FOR REAL TIME APPLICATION
, 2019 Many tone mapping algorithms for natural and synthetic images have been proposed in recent years. However, manually tuning their parameters is difficult, especially if the scene is dynamically changing over time or the view point is altered, as is the ...
Zhao, Siwei
core