Results 171 to 180 of about 1,605,291 (333)
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
THE PITUITARY GLAND AND THE VASCULAR TONE OF THE KIDNEY [PDF]
L Brull, D Louis-Bar
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
An outline of Lulubo phonology
This article outlines the phonology of Lulubo, a little known Central Sudanic language spoken in the southern Sudan. An account is given of the phonemic inventory (vowels, consonants, and tones), vowel harmony, syllable structure, special features of ...
Torben Andersen
doaj
Theoretical studies of tone noise from a fan rotor [PDF]
An analytical study was made of some possible rotor alone noise sources of dipole, quadrapole and monopole characters which generate discrete tone noise.
Chu, W. T.+2 more
core +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
The Relation of Pitch to the Duration of a Tone [PDF]
S. S. Stevens, Anna-Lena Ekdahl
openalex +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source