Results 191 to 200 of about 677,362 (304)

Speech comprehension in a tone language: The role of lexical tone, context, and intonation in Cantonese-Chinese

, 2018
C Kung
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Exposure to the herbicide glyphosate leads to inappropriate threat responses and alters gut microbial composition. [PDF]

Front Toxicol
Cáceres-Chacón M, Martínez-Guzmán O, Haddock-Martínez HA, Figueroa-Pérez A, Rodríguez-Rosado S, Suárez-Pérez J, Ramos-Sánchez RY, Godoy-Vitorino F, Sierra-Mercado D.   +8 more
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Neural Discrimination of Temporal Patterns-Associations to Dyslexia Risk, Language Abilities, and Music Activities. [PDF]

Ann N Y Acad Sci
Virtala P, Navarrete-Arroyo S, Partanen E, Huotilainen M, Kujala T.   +4 more
europepmc   +1 more source

Sodium reduction and weight loss in the treatment of hypertension in older persons: a randomized controlled trial of nonpharmacologic interventions in the elderly (TONE). TONE Collaborative Research Group.

Journal of the American Medical Association (JAMA), 1998
P. Whelton, L. Appel, M. Espeland, W. Applegate, W. Ettinger, J. Kostis, S. Kumanyika, S. Kumanyika, C. Lacy, K. Johnson, S. Folmar, J. Cutler   +11 more
semanticscholar   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Selective Listening to Unpredictable Sound Sequences Increases Tonic Muscle Activity in the Human Vestigial Auriculomotor System. [PDF]

eNeuro
Mai A, Hillyard SA, Strauss DJ, Corona-Strauss FI.   +3 more
europepmc   +1 more source

Implicit memory for rhythmic tone sequence: A pilot study on perceptual priming for short temporal pattern.

, 2001
Yasuhiro Gotô
openalex   +2 more sources