Results 231 to 240 of about 1,724,932 (347)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Differences in firing patterns along the dorsal-intermediate hippocampal axis in a fixed route during a change in emotional context. [PDF]

Front Syst Neurosci
Troha R, Lee SLT, Anam M, Tavakoli S, Morte B, Stevenson IH, Markus EJ.   +6 more
europepmc   +1 more source

Pure-tone hearing levels according to age.

, 1989
Makito Okamoto, Tetsuya Shitara, Yasuhiro Momiyama, Masatoshi Hirayama, T. Ishii   +4 more
openalex   +2 more sources

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Distinct neural signatures in a sensorimotor synchronization-continuation task. [PDF]

Imaging Neurosci (Camb)
Kim DJ, Bolbecker AR, Moussa-Tooks AB, Wisner KM, O'Donnell BF, Gildea EL, Hetrick WP.   +6 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

<i>In vitro</i> study of spontaneous motility and cholinergic responses in the human Hirschsprung's disease colon. [PDF]

Front Pediatr
Schulze F, Lindert J, Köhling R, Märzheuser S, Kirschstein T.   +4 more
europepmc   +1 more source

Screening method of nonorganic deafness using pure tone audiometer.

, 1996
Hitoshi Saitô
openalex   +2 more sources

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Novelty Influences Dopamine Responses to Conditioned and Unconditioned Aversive Stimuli over Extended Temporal Windows. [PDF]

eNeuro
Kutlu MG, Cajigas Gabriel SA, Tat J, Zachry JE, Calipari ES.   +4 more
europepmc   +1 more source