Results 51 to 60 of about 395,145 (308)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The borrowing of aspects as lexical tone classes Y-intial Tuareg verbs in Tasawaq
In Tasawaq, a Northern Songhay language of Niger, there exists a lexical tone class distinction between stative and active verbs. This tone class distinction only exists in one class of verbs borrowed from Tuareg, verbs with an initial y-.
Maarten Kossmann
doaj +3 more sources
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The Roles of Segments and Tone in Mandarin Lexical Processing: An ERP Study
Backgrounds: Segments and tone are important sub-syllabic units that play large roles in lexical processing in tonal languages. However, their roles in lexical processing remain unclear, and the event-related potential (ERP) technique will benefit the ...
Dan Du, Minghu Jiang
doaj +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
L’ironie : « violation » ou « transgression » des maximes conversationnelles ?
Dans le présent article, nous nous proposons de décrire ce qu’est la transgression ressentie dans les énoncés ironiques en général (ironie standard et non-standard) dans le cadre de la théorie argumentative de la polyphonie (TAP), et de montrer qu’il s ...
Tomonori Okubo
doaj
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
COMPARISON OF THE EFFECT OF TRANSCRANIAL STIMULATION OF PRIMARY MOTOR CORTEX (M1) AND RELAXATION TONE AND MINDFULNESS-BASED BREATHING (MBMR) ON GROUND REACTION FORCE OF LOWER LIMB DURING WALKING IN SUBJECTS WITH PATELLOFEMORAL PAIN [PDF]
Hamed Mohmadi +2 more
openalex +1 more source

