Results 51 to 60 of about 492,852 (312)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

TONES IN WAKASHAN

open access: yesLinguistics, 1975
1. In the summer of 1972 I spent ten weeks in the village of Klemtu, B.C., where I studied the Heiltsuk language. During this period I collected a vocabulary of over 4000 words. My main Informant was Mr. William Freeman. The investigation was financed by the Netherlands Organization for the Advancement of Pure Research (Z.W.O.).
openaire   +2 more sources

Relating production and perception of L2 tone: supplementary materials

open access: yes, 2020
This dataset contains supplementary materials to the paper "Relating the production and perception of L2 tone". It includes anonymised perception and production data (as CSV files) and R code to reproduce the figures and analyses described in the paper ...
Đinh Lư Giang, Kirby, James
core   +1 more source

“Mirror, mirror…” A preliminary investigation of skin tone dissatisfaction and its impact among British adults [PDF]

open access: yes, 2013
This study examined skin tone dissatisfaction, measured using a skin tone chart, among a multiethnic sample of British adults. A total of 648 British White individuals, 292 British South Asians, and 260 British African Caribbean participants completed a ...
Henry, A.   +4 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Efficient implementation of pilot-aided 32 QAM for fixed wireless and mobile ISDN applications [PDF]

open access: yes, 2000
This paper presents the design and performance of a pilot tone-aided 32 QAM modem developed for wireless ISDN applications. The modem is capable of transmitting a gross data rate of 70 kbit/s in a 20 kHz channel spacing.
Nix, AR, Tariq,, Fahim, Love, D
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A spin to preserve contrast: Taiwanese tone sandhi

open access: yesStellenbosch Papers in Linguistics Plus, 2020
Chain-shifts, particularly circular ones such as the tone sandhi of Taiwanese Min has been a longstanding challenge to which phonologists of various persuasions have attempted. This paper appeals to markedness against contour tones in non-final positions
Wee, Lian-Hee
doaj   +1 more source

Tone and Intonation in Chichewa and Tumbuka

open access: yes, 2016
This study compares the tone and intonation systems of two closely related Bantu languages spoken in Malawi, Chichewa and Tumbuka. The lexical tone systems of the two languages are quite different from each other.
Downing, Laura J.,, Laura J. Downing
core   +1 more source

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