Results 91 to 100 of about 807,723 (325)
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
A comparison of laser-based ranging systems for AR/C [PDF]
The three most common types of laser target ranging (time-of-flight, tone modulated, and FM-CW) are discussed in terms of principle of operation.
Goode, Pleasant W., IV +1 more
core +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
THE LANGUAGE OF CORPORATE ENVIRONMENTAL DISCLOSURE: A RESEARCH NOTE [PDF]
We investigate different language techniques used in corporate environmental disclosures and test whether the impression management (see Neu et al., 1998) hypothesis holds when disclosures are measured as such.
Charles H. Cho, Robin W. Roberts
core
Frontiers in PsychologyObjectiveThis study aims to precisely model the nonlinear relationship between university students’ literature reading preferences (LRP) and their levels of anxiety and depression using a multilayer perceptron (MLP) to identify reading-related risk ...
Yamei Liu
doaj +1 more source
La Bretagne Linguistique, 2015 Despite its considerable volume of production and extensive readership, regionalist literature is created within a process of discredit, of exclusion from literary histories and even of disdain for its lack of universalising ambition and its role in the ...
Thierry Glon
doaj +1 more source
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
A tonal analysis of contemporary Tai Khuen varieties
, 2012 This paper presents an analysis of the tones of five contemporary Tai Khuen varieties in order to investigate the differences in the number of distinctive tones reported in the literature.
Owen, R. Wyn
core
Literal Translation and the Materiality of Language: Lu Xun as a Case [PDF]
, 2012 With his insistence upon the literal rendering in Chinese of foreign texts, especially regarding syntax, Lu Xun’s understanding of “literal translation” strikes a rather distinct note in the modern Chinese literary scene. The intention behind this method,
Cui, Wenjin
core +1 more source