Results 111 to 120 of about 6,095,243 (366)
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Combinatorics in the Art of the Twentieth Century [PDF]
This paper is motivated by a question I asked myself: How can combinatorial structures be used in a work of art? Immediately, other questions arose: Whether there are artists that work or think combinatorially?
Barrière Figueroa, Eulalia
core
Previous studies reported a non-native word learning advantage for bilingual infants at around 18 months. We investigated developmental changes in infant interpretation of sounds that aid in object mapping.
Liquan Liu, R. Kager
semanticscholar +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
THE LANGUAGE OF CORPORATE ENVIRONMENTAL DISCLOSURE: A RESEARCH NOTE [PDF]
We investigate different language techniques used in corporate environmental disclosures and test whether the impression management (see Neu et al., 1998) hypothesis holds when disclosures are measured as such.
Charles H. Cho, Robin W. Roberts
core
Background. Research literature highlights the need to use objective assessment tools to quantify muscle tone because all typically used clinical scales of muscle tone have reliability problems.
Triinu Sakkool +2 more
doaj +1 more source
Speech perception is a multisensory process: what we hear can be affected by what we see. For instance, the McGurk effect occurs when auditory speech is presented in synchrony with discrepant visual information.
Yueqiao Han +3 more
semanticscholar +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Impressionistic techniques applied in sound art & design [PDF]
Sound art and design collectively refer to the process of specifying, acquiring, manipulating or generating sonic elements to evoke emotion and environment.
Sapp, Kaitlyn E. M.
core
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source

